Q5N4Y0 (Q5N4Y0_SYNP6) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chromosomal replication initiator protein DnaA HAMAP MF_00377

Gene names

Name:	dnaA HAMAP MF_00377 EMBL BAD78639.1
Ordered Locus Names:	syc0449_d

Organism

Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans) [Complete proteome] [HAMAP]

Taxonomic identifier

269084 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	482 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377 RuleBase RU000577
Subcellular location	Cytoplasm By similarity HAMAP MF_00377.
Sequence similarities	Belongs to the DnaA family. HAMAP MF_00377 RuleBase RU004227

Ontologies

Keywords
Biological process	DNA replication HAMAP MF_00377 RuleBase RU000577
Cellular component	Cytoplasm HAMAP MF_00377
Ligand	ATP-binding HAMAP MF_00377 RuleBase RU000577 DNA-binding HAMAP MF_00377 RuleBase RU000577 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA-dependent DNA replication initiation Inferred from electronic annotation. Source: HAMAP regulation of DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA replication origin binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	185 – 192	8	ATP By similarity HAMAP MF_00377

Sequences

	Sequence		Length	Mass (Da)
	Q5N4Y0 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: A31375184B47699E	FASTA	482	54,140
	10 20 30 40 50 60 MRRGKKVGGI VLIPYSAAIA VEQSLEHLWE QILERLQHQL SRPTFETWIK TATAEAFDGK 70 80 90 100 110 120 VLRLSTPNPF ARNWLQKYYL RTIADVAAEI LGHGIELQIG VLSDTSAEPE SGAELWPAIS 130 140 150 160 170 180 PPPAVEVVKP PTTTAGRPPL RSSDLNPKYV FSRFVVGAYN RMAHAASLAI AEYPGREYNP 190 200 210 220 230 240 LFLCGGVGLG KTHLMQAIGH YRLEIDPDAK IFYVSTEQFT NDLIAAIRRD SMQSFREHYR 250 260 270 280 290 300 AADVIMVDDI QFIEGKEYTQ EEFFYTFNSL HEAGKQIVLA SDRPPSQIPR LQERLISRFS 310 320 330 340 350 360 MGLIADIQPP DFETRVAILQ KKSEFENMPL PRDVIEYIAA RYTSNIRELE GALTRAVAYA 370 380 390 400 410 420 SISGLALTLA NIAPVLTPPT EKMELSPEMI LQTVAETFDV SIEDLRGNSR RREVSLARQV 430 440 450 460 470 480 GMYLMRQHTD LSLPKIGEQF GGKDHTTVMY SCEKIGQLRQ SDPQMGKQLQ EINDQLFVAS RG

References

[1]

"Complete nucleotide sequence of the freshwater unicellular cyanobacterium Synechococcus elongatus PCC 6301 chromosome: gene content and organization." Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M., Kanehisa M., Omata T., Sugiura M., Sugita M. Photosyn. Res. 93:55-67(2007) [PubMed: 17211581] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008231 Genomic DNA. Translation: BAD78639.1.
RefSeq	YP_171159.1. NC_006576.1.
3D structure databases
ProteinModelPortal	Q5N4Y0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5N4Y0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3197938.
GenomeReviews	Gene locus syc0449_d in contig AP008231_GR.
KEGG	syc:syc0449_d.
PATRIC	32486484. VBISynElo117686_0516.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0593.
HOGENOM	HBG695666.
OMA	CHTLNAL.
PhylomeDB	Q5N4Y0.
ProtClustDB	PRK00149.
Enzyme and pathway databases
BioCyc	SELO269084:SYC0449_D-MONOMER.
Family and domain databases
HAMAP	MF_00377. DnaA_bact. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR001957. Chromosome_initiator_DnaA. IPR020591. Chromosome_initiator_DnaA-like. IPR018312. Chromosome_initiator_DnaA_CS. IPR013159. DnaA_C. IPR013317. DnaA_Hda. IPR010921. Trp_repressor/repl_initiator. [Graphical view]
Gene3D	G3DSA:1.10.1750.10. DnaA_C. 1 hit.
KO	K02313.
Pfam	PF00308. Bac_DnaA. 1 hit. PF08299. Bac_DnaA_C. 1 hit. [Graphical view]
PRINTS	PR00051. DNAA.
SMART	SM00382. AAA. 1 hit. SM00760. Bac_DnaA_C. 1 hit. [Graphical view]
SUPFAM	SSF48295. Trp_repress_rep. 1 hit.
TIGRFAMs	TIGR00362. DnaA. 1 hit.
PROSITE	PS01008. DNAA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5N4Y0_SYNP6

Accession

Primary (citable) accession number: Q5N4Y0

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	December 14, 2011
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)