Q5N4G9 (Q5N4G9_SYNP6) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid A disaccharide synthase EMBL BAD78800.1

Gene names

Name:	lpxB EMBL BAD78800.1
Ordered Locus Names:	syc0610_c

Organism

Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans) [Complete proteome] [HAMAP]

Taxonomic identifier

269084 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5N4G9 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: 1009DAB160A08B21	FASTA	399	43,916
	10 20 30 40 50 60 MAAIRLFIST GEVSGDLQGS LLIAALFRQA KQLGLELEIL ALGGDRMAAA GAKLLANTIG 70 80 90 100 110 120 ISSIGIWEAL PYVWPTWRLQ QKIARQIRET SLDAAILIDY IGPNIGWGGR LPKSHPNIPI 130 140 150 160 170 180 FYYIAPQEWV WSFGEGKTTQ LVNFSDRIFA IFPGEATYYR DRGAAVSFVG HPLIDQLQDR 190 200 210 220 230 240 PDRAKARAQL GLQEQERAIA LYPASRPQEL KFLLPTVLAA AQQLNAELPN LRFFVPLSQE 250 260 270 280 290 300 KFRTTIEEAA RELNLPLQIV SGETTALVQA AADLAIAKSG TVNLELGLQG IPQVVVYRVG 310 320 330 340 350 360 AVTAWIARHI LRFSIPFMSP VNLVDMEAIV PELLQDEANP DRIAAEAKAI LLDPDRQAAI 370 380 390 QAGYQRMRQS LGEPGVCDRA AQEILTAALQ QKQVLSRER

References

[1]

"Complete nucleotide sequence of the freshwater unicellular cyanobacterium Synechococcus elongatus PCC 6301 chromosome: gene content and organization." Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M., Kanehisa M., Omata T., Sugiura M., Sugita M. Photosyn. Res. 93:55-67(2007) [PubMed: 17211581] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008231 Genomic DNA. Translation: BAD78800.1.
RefSeq	YP_171320.1. NC_006576.1.
3D structure databases
ProteinModelPortal	Q5N4G9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5N4G9.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3199963.
GenomeReviews	Gene locus syc0610_c in contig AP008231_GR.
KEGG	syc:syc0610_c.
PATRIC	32486860. VBISynElo117686_0704.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0763.
HOGENOM	HBG584837.
OMA	PDFNLGL.
PhylomeDB	Q5N4G9.
ProtClustDB	PRK00025.
Enzyme and pathway databases
BioCyc	SELO269084:SYC0610_C-MONOMER.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q5N4G9_SYNP6

Accession

Primary (citable) accession number: Q5N4G9

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)