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Q5N3D4 (AROB_SYNP6) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:syc0996_d
OrganismSynechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans) [Complete proteome] [HAMAP]
Taxonomic identifier269084 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length368 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3683683-dehydroquinate synthase HAMAP MF_00110
PRO_0000231137

Sequences

Sequence LengthMass (Da)Tools
Q5N3D4 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 654976F188FE0B51

FASTA36839,575
        10         20         30         40         50         60 
MSVQIPVALP QNAYEIAIAN GGLAAAGTWL QQADLKAGTK LLIVTNPAIG RRYGDRLVAA 

        70         80         90        100        110        120 
LQEAGFIVDC LTLPAGERYK TPATVQRIYD KALELRLERR SALVALGGGV IGDMTGFAAA 

       130        140        150        160        170        180 
TWLRGISFVQ IPTSLLAMVD ASIGGKTGVN HPRGKNLIGA FHQPKLVLID PETLQTLPVR 

       190        200        210        220        230        240 
EFRAGMAEVI KYGVIWDRDL FERLEASPFL DRPRSLPANL LTLILERSCR AKAEVVAKDE 

       250        260        270        280        290        300 
KESGLRAILN YGHTIGHAVE SLTGYRIVNH GEAVAIGMVA AGRLAVALGL WNQDECDRQE 

       310        320        330        340        350        360 
AVIAKAGLPT RLPEGIDQAA IVEALQLDKK VQAGKVRFIL PTTLGHVTIT DQVPSQTLQE 


VLQAIANP

« Hide

References

[1]"Complete nucleotide sequence of the freshwater unicellular cyanobacterium Synechococcus elongatus PCC 6301 chromosome: gene content and organization."
Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M., Kanehisa M., Omata T., Sugiura M., Sugita M.
Photosyn. Res. 93:55-67(2007) [PubMed: 17211581] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27144 / PCC 6301 / SAUG 1402/1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008231 Genomic DNA. Translation: BAD79186.1.
RefSeqYP_171706.1. NC_006576.1.

3D structure databases

ProteinModelPortalQ5N3D4.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5N3D4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3198269.
GenomeReviewsGene locus syc0996_d in contig AP008231_GR.
KEGGsyc:syc0996_d.
PATRIC32487800. VBISynElo117686_1160.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBQ5N3D4.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycSELO269084:SYC0996_D-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_SYNP6
AccessionPrimary (citable) accession number: Q5N3D4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: February 1, 2005
Last modified: January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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