Q5N1I3 (SYGA_SYNP6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	syc1647_c

Organism

Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans) [Complete proteome] [HAMAP]

Taxonomic identifier

269084 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 292	292	Glycine--tRNA ligase alpha subunit HAMAP MF_00254		PRO_1000047515

Sequences

	Sequence		Length	Mass (Da)
	Q5N1I3 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: 676BC28734E27C4F	FASTA	292	33,727
	10 20 30 40 50 60 MNFQSVIATL NQFWADRGCL IAQPYDTEKG AGTMNPHTFL RAIGPEPWAV AYVEPCRRPT 70 80 90 100 110 120 DGRYGENPNR YQHYYQYQVL IKPSPEGIQE TYLDSLRALG IQPEEHDIRF VEDNWESPTL 130 140 150 160 170 180 GAWGVGWEVW LDGMEVAQFT YFQQCGGIDC RPVSIEITYG LERLAMYLQN VEAFTEIKWT 190 200 210 220 230 240 DRLSYGDVHL QSEIEQCTYN FEASTPELLF QLFGLYEQEA TQLIEKGLVH PSLDYVLKCS 250 260 270 280 290 HSFNLLDARG LISVTERTRY IGRIRNMARQ VAKLYLEQRE QLGFPLLQKV TA

References

[1]

"Complete nucleotide sequence of the freshwater unicellular cyanobacterium Synechococcus elongatus PCC 6301 chromosome: gene content and organization." Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M., Kanehisa M., Omata T., Sugiura M., Sugita M. Photosyn. Res. 93:55-67(2007) [PubMed: 17211581] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27144 / PCC 6301 / SAUG 1402/1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008231 Genomic DNA. Translation: BAD79837.1.
RefSeq	YP_172357.1. NC_006576.1.
3D structure databases
HSSP	HSSP built from PDB template 1J5W based on UniProtKB Q9WY59.
ProteinModelPortal	Q5N1I3.
SMR	Q5N1I3. Positions 1-277.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5N1I3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3199305.
GenomeReviews	Gene locus syc1647_c in contig AP008231_GR.
KEGG	syc:syc1647_c.
PATRIC	32489287. VBISynElo117686_1886.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0752.
HOGENOM	HBG285316.
OMA	CRRPTDG.
PhylomeDB	Q5N1I3.
ProtClustDB	PRK09348.
Enzyme and pathway databases
BioCyc	SELO269084:SYC1647_C-MONOMER.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
KO	K01878.
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. GlyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_SYNP6

Accession

Primary (citable) accession number: Q5N1I3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 1, 2005
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program