Reviewed, UniProtKB/Swiss-Prot Q5N133 (PPNK1_SYNP6)

Names and origin

Protein names

Recommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase 1
      Short name=Poly(P)/ATP NAD kinase 1
    EC=2.7.1.23

Gene names

Name:	ppnK1
Ordered Locus Names:	syc1797_c

Organism

Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans) [Complete proteome] [HAMAP]

Taxonomic identifier

269084 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361
Subcellular location	Cytoplasm By similarity HAMAP MF_00361.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 305	305	Probable inorganic polyphosphate/ATP-NAD kinase 1 HAMAP MF_00361		PRO_0000229701

Sequences

	Sequence		Length	Mass (Da)
	Q5N133-1 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: 2CA654EED5412A6C	FASTA	305	33,422
	10 20 30 40 50 60 MPDVGIIYND SKPRACTIAE ELQQQLQDRG WGVRLATSQS GLLGYSNPDT VICHTPVESL 70 80 90 100 110 120 VPRGFDASLR WAIVLGGDGT VLAAARQLAP IGVPMLTVNT GHLGFLAEAY LDSLPAAIEQ 130 140 150 160 170 180 LCKGEYSIEE RTMMEVKVLR RELIRWEALS LNEMALHREP LTSMCHFEVA IGKHVPVDIA 190 200 210 220 230 240 ADGVIVSTPT GSTAYSLSSG GPVVTPDVPV FQLVPICPHS LASRALVFAN REPMTIFPAT 250 260 270 280 290 300 PERLMMVVDG NAGCYVWPED RVLIQRSRYP AQFIRLQPNE FFRVLREKLG WGLPHVAKPS APDQS

References

[1]

"Complete nucleotide sequence of the freshwater unicellular cyanobacterium Synechococcus elongatus PCC 6301 chromosome: gene content and organization." Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M., Kanehisa M., Omata T., Sugiura M., Sugita M. Photosyn. Res. 93:55-67(2007) [PubMed: 17211581] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008231 Genomic DNA. Translation: BAD79987.1.
RefSeq	YP_172507.1.
3D structure databases
SMR	Q5N133. Positions 3-293.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5N133.
Genome annotation databases
GeneID	3198905.
GenomeReviews	Gene locus syc1797_c in contig AP008231_GR.
KEGG	syc:syc1797_c.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0061.
HOGENOM	HBG713904.
OMA	HIDASID.
PhylomeDB	Q5N133.
Enzyme and pathway databases
BioCyc	SELO269084:SYC1797_C-MONOMER.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. ATP_NADK. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPNK1_SYNP6

Accession

Primary (citable) accession number: Q5N133

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	February 1, 2005
Last modified:	January 19, 2010
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)