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Q5N013 (DAPF_SYNP6) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Diaminopimelate epimerase
Short name=DAP epimerase
EC=5.1.1.7
Gene names
Name:dapF
Ordered Locus Names:syc2167_c
OrganismSynechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans) [Complete proteome] [HAMAP]
Taxonomic identifier269084 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length280 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197

Subcellular location

Cytoplasm By similarity HAMAP MF_00197.

Sequence similarities

Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Lysine biosynthesis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlysine biosynthetic process via diaminopimelate

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondiaminopimelate epimerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 280280Diaminopimelate epimerase HAMAP MF_00197
PRO_1000011976

Sites

Active site751 By similarity
Active site2221 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5N013 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 028A3310F9437BAC

FASTA28029,971
        10         20         30         40         50         60 
MSLQFAKYHG LGNDFILVDN RESGEPRLTP EQAVQVCDRN FGVGADGVIF ALPGSGDSDY 

        70         80         90        100        110        120 
VMRIFNSDGS EPEMCGNGIR CLAKFLSELD GGAQSRYRIA TGAGLIVPTL TETGLVTVDM 

       130        140        150        160        170        180 
GPAYLKPVEI PTTLTGTGDR VVEADLEVGD RPWKVTTVSM GNPHCITFVE DVAAVPLAEI 

       190        200        210        220        230        240 
GPLFEHHPVF PQRTNTEFVE VVRPDYLKMR VWERGAGATL ACGTGACATL VAAVLTGRSD 

       250        260        270        280 
RQATVELPGG PLQIEWREDG HLFMTGPAVK VFSGSMELAA

« Hide

References

[1]"Complete nucleotide sequence of the freshwater unicellular cyanobacterium Synechococcus elongatus PCC 6301 chromosome: gene content and organization."
Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M., Kanehisa M., Omata T., Sugiura M., Sugita M.
Photosyn. Res. 93:55-67(2007) [PubMed: 17211581] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27144 / PCC 6301 / SAUG 1402/1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008231 Genomic DNA. Translation: BAD80357.1.
RefSeqYP_172877.1. NC_006576.1.

3D structure databases

HSSPHSSP built from PDB template 2GKE based on UniProtKB P44859.
ProteinModelPortalQ5N013.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5N013.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3200209.
GenomeReviewsGene locus syc2167_c in contig AP008231_GR.
KEGGsyc:syc2167_c.
PATRIC32490478. VBISynElo117686_2469.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0253.
HOGENOMHBG399442.
OMAFMTGPAT.
PhylomeDBQ5N013.
ProtClustDBPRK00450.

Enzyme and pathway databases

BioCycSELO269084:SYC2167_C-MONOMER.

Family and domain databases

HAMAPMF_00197. DAP_epimerase.
[Tree]
InterProIPR018510. DAP_epimerase_AS.
IPR001653. DAP_epimerase_DapF.
[Graphical view]
KOK01778.
PfamPF01678. DAP_epimerase. 2 hits.
[Graphical view]
TIGRFAMsTIGR00652. DapF. 1 hit.
PROSITEPS01326. DAP_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPF_SYNP6
AccessionPrimary (citable) accession number: Q5N013
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 1, 2005
Last modified: January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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