Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q5MZF8

- Q5MZF8_SYNP6

UniProt

Q5MZF8 - Q5MZF8_SYNP6

Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (01 Feb 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciSELO269084:GCDQ-2428-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Name:icdImported
    Ordered Locus Names:syc2372_dImported
    OrganismiSynechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis nidulans)Imported
    Taxonomic identifieri269084 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
    ProteomesiUP000001175: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi269084.syc2372_d.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5MZF8.
    SMRiQ5MZF8. Positions 4-473.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0538.
    HOGENOMiHOG000021113.
    KOiK00031.
    OMAiCLRPIRY.
    OrthoDBiEOG6SNDTP.

    Family and domain databases

    Gene3Di3.40.718.10. 2 hits.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5MZF8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYEKIQPPSE GSKIRFEAGK PIVPDNPIIP FIRGDGAGVD IWPATERVLD    50
    AAVAKAYGGQ RKITWFKVYA GDEACDLYGT YQYLPEDTLT AIREYGVAIK 100
    GPLTTPIGGG IRSLNVALRQ IFDLYACVRP CRYYTGTPSP HRTPEQLDVV 150
    VYRENTEDIY LGIEWKQGDP TGDRLIKLLN EDFIPNSPSL GKKQIRLDSG 200
    IGIKPISKTG SQRLIRRAIE HALRLEGRKR HVTLVHKGNI MKFTEGAFRD 250
    WGYELATTEF RTDCVTERES WILANQESKP DLSLEDNARL IEPGYDAMTP 300
    EKQAAVVAEV KAVLDSIGAT HGNGQWKSKV LVDDRIADSI FQQIQTRPGE 350
    YSVLATMNLN GDYISDAAAA VVGGLGMAPG ANIGDEAAIF EATHGAAPKH 400
    AGLDRINPGS VILSGVMMLE YLGWQEAADL ITKGISQAIA NREVTYDLAR 450
    LMEPAVDQPL KCSEFAEAIV KHFDD 475
    Length:475
    Mass (Da):52,233
    Last modified:February 1, 2005 - v1
    Checksum:i28B338A22905C8FC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008231 Genomic DNA. Translation: BAD80562.1.
    RefSeqiYP_173082.1. NC_006576.1.

    Genome annotation databases

    EnsemblBacteriaiBAD80562; BAD80562; syc2372_d.
    GeneIDi3198034.
    KEGGisyc:syc2372_d.
    PATRICi32490936. VBISynElo117686_2698.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008231 Genomic DNA. Translation: BAD80562.1 .
    RefSeqi YP_173082.1. NC_006576.1.

    3D structure databases

    ProteinModelPortali Q5MZF8.
    SMRi Q5MZF8. Positions 4-473.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 269084.syc2372_d.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAD80562 ; BAD80562 ; syc2372_d .
    GeneIDi 3198034.
    KEGGi syc:syc2372_d.
    PATRICi 32490936. VBISynElo117686_2698.

    Phylogenomic databases

    eggNOGi COG0538.
    HOGENOMi HOG000021113.
    KOi K00031.
    OMAi CLRPIRY.
    OrthoDBi EOG6SNDTP.

    Enzyme and pathway databases

    BioCyci SELO269084:GCDQ-2428-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 2 hits.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete nucleotide sequence of the freshwater unicellular cyanobacterium Synechococcus elongatus PCC 6301 chromosome: gene content and organization."
      Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M., Kanehisa M., Omata T., Sugiura M., Sugita M.
      Photosyn. Res. 93:55-67(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 27144 / PCC 6301 / SAUG 1402/1Imported.

    Entry informationi

    Entry nameiQ5MZF8_SYNP6
    AccessioniPrimary (citable) accession number: Q5MZF8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 1, 2005
    Last sequence update: February 1, 2005
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3