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Protein

Zinc finger protein 667

Gene

Znf667

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri144 – 16623C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri172 – 19423C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri200 – 22223C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri253 – 27523C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri328 – 35023C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri356 – 37823C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri384 – 40623C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri413 – 43523C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri441 – 46323C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri469 – 49123C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri497 – 51923C2H2-type 11PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri525 – 54723C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri553 – 57523C2H2-type 13PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri581 – 60323C2H2-type 14PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 667
Alternative name(s):
Myocardial ischemic preconditioning up-regulated protein 1
Gene namesi
Name:Znf667
Synonyms:Mip1, Mipu1, Zfp667
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1359114. Zfp667.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 608608Zinc finger protein 667PRO_0000251899Add
BLAST

Expressioni

Gene expression databases

ExpressionAtlasiQ5MYW4. baseline.
GenevisibleiQ5MYW4. RN.

Structurei

3D structure databases

ProteinModelPortaliQ5MYW4.
SMRiQ5MYW4. Positions 438-492, 522-603.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 8572KRABPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 14 C2H2-type zinc fingers.PROSITE-ProRule annotation
Contains 1 KRAB domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri144 – 16623C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri172 – 19423C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri200 – 22223C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri253 – 27523C2H2-type 4PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri328 – 35023C2H2-type 5PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri356 – 37823C2H2-type 6PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri384 – 40623C2H2-type 7PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri413 – 43523C2H2-type 8PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri441 – 46323C2H2-type 9PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri469 – 49123C2H2-type 10PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri497 – 51923C2H2-type 11PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri525 – 54723C2H2-type 12PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri553 – 57523C2H2-type 13PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri581 – 60323C2H2-type 14PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

GeneTreeiENSGT00390000021477.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiQ5MYW4.
KOiK09228.
PhylomeDBiQ5MYW4.
TreeFamiTF341817.

Family and domain databases

Gene3Di3.30.160.60. 14 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 1 hit.
PF13912. zf-C2H2_6. 2 hits.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 14 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 14 hits.
PS50157. ZINC_FINGER_C2H2_2. 14 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5MYW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAARGKSKS KAPVTFGDLA IYFSQEEWEW LSPNQKDLYE DVMLENYHNL
60 70 80 90 100
VSVGLACRRP NIIALLEKGK APWMVEPSRK RRGPELGSKD ETKKLPPSQC
110 120 130 140 150
NKSGPSICKK PDSSQQKVPT EKAKHNKNAV PRKNKKGHSG KKSLKCNSCG
160 170 180 190 200
KTFFRSLSLK LHQGFHTGER SYECSTCGQV FRQILSLILH QRVHTQNKSY
210 220 230 240 250
ECDKCGDIFN KKLTLMIHRR SHNGKENFHH EKTSDSCPSL SPHHNNHAID
260 270 280 290 300
SIHQCRKCGK VFSRMSSLLL HKKIHNRKRI QKYSACGRGF KKKPVLVHKR
310 320 330 340 350
ICIGKKTHEN KALIQSLRQR TYQSENPFTC RKCRKSFSRI SALMLHQRAH
360 370 380 390 400
TSGNPYKCDK CQKDFGRLST LILHLRIHSG EKQFKCNKCE KVCNRLSSFI
410 420 430 440 450
QHKKIHKRKK KLIECKECGK MFGGMKNLKV HLNIHSEEKP FKCNKCSKVF
460 470 480 490 500
GRQSFLSEHQ RIHTGEKPYQ CEECGKAFSH RISLTRHKRI HSEDRPYECD
510 520 530 540 550
LCGKAFSQSA HLAQHERIHT GEKPYACKIC KKSFTQRISL ILHERSHTGE
560 570 580 590 600
KPYECNECGK AFSSGSDLIR HQRSHSSEKP YECSKCGKAY SRSSSLIRHQ

SIHSEEMS
Length:608
Mass (Da):70,038
Last modified:February 1, 2005 - v1
Checksum:i99BB8EB373514ED5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY221750 mRNA. Translation: AAO67708.1.
RefSeqiNP_001008557.1. NM_001008557.1.
XP_006228251.1. XM_006228189.2.
UniGeneiRn.43493.

Genome annotation databases

EnsembliENSRNOT00000063956; ENSRNOP00000061115; ENSRNOG00000033906.
GeneIDi308326.
KEGGirno:308326.
UCSCiRGD:1359114. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY221750 mRNA. Translation: AAO67708.1.
RefSeqiNP_001008557.1. NM_001008557.1.
XP_006228251.1. XM_006228189.2.
UniGeneiRn.43493.

3D structure databases

ProteinModelPortaliQ5MYW4.
SMRiQ5MYW4. Positions 438-492, 522-603.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000063956; ENSRNOP00000061115; ENSRNOG00000033906.
GeneIDi308326.
KEGGirno:308326.
UCSCiRGD:1359114. rat.

Organism-specific databases

CTDi384763.
RGDi1359114. Zfp667.

Phylogenomic databases

GeneTreeiENSGT00390000021477.
HOGENOMiHOG000234617.
HOVERGENiHBG018163.
InParanoidiQ5MYW4.
KOiK09228.
PhylomeDBiQ5MYW4.
TreeFamiTF341817.

Miscellaneous databases

PROiQ5MYW4.

Gene expression databases

ExpressionAtlasiQ5MYW4. baseline.
GenevisibleiQ5MYW4. RN.

Family and domain databases

Gene3Di3.30.160.60. 14 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 1 hit.
PF13912. zf-C2H2_6. 2 hits.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 14 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 14 hits.
PS50157. ZINC_FINGER_C2H2_2. 14 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning and characterization of a new gene Mip1 up-regulated during myocardial ischemia-reperfusion."
    Yuan C., Zhang H., Liu Y., Wang Q., Xiao X.
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Jin Zhan 31:231-236(2004)
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: Wistar.

Entry informationi

Entry nameiZN667_RAT
AccessioniPrimary (citable) accession number: Q5MYW4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: February 1, 2005
Last modified: June 8, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.