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Protein

Zinc finger protein 667

Gene

Znf667

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri144 – 166C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri172 – 194C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri200 – 222C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri253 – 275C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri328 – 350C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri356 – 378C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri384 – 406C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri413 – 435C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri441 – 463C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri469 – 491C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri497 – 519C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri525 – 547C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri553 – 575C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri581 – 603C2H2-type 14PROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 667
Alternative name(s):
Myocardial ischemic preconditioning up-regulated protein 1
Gene namesi
Name:Znf667
Synonyms:Mip1, Mipu1, Zfp667
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1359114 Zfp667

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002518991 – 608Zinc finger protein 667Add BLAST608

Expressioni

Gene expression databases

BgeeiENSRNOG00000033906
GenevisibleiQ5MYW4 RN

Structurei

3D structure databases

ProteinModelPortaliQ5MYW4
SMRiQ5MYW4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 85KRABPROSITE-ProRule annotationAdd BLAST72

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri144 – 166C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri172 – 194C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri200 – 222C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri253 – 275C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri328 – 350C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri356 – 378C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri384 – 406C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri413 – 435C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri441 – 463C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri469 – 491C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri497 – 519C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri525 – 547C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri553 – 575C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri581 – 603C2H2-type 14PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

GeneTreeiENSGT00390000021477
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiQ5MYW4
KOiK09228
OMAiVCNRHSS
OrthoDBiEOG091G02KC
PhylomeDBiQ5MYW4
TreeFamiTF341817

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 14 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 9 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 14 hits
PS50157 ZINC_FINGER_C2H2_2, 14 hits

Sequencei

Sequence statusi: Complete.

Q5MYW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAARGKSKS KAPVTFGDLA IYFSQEEWEW LSPNQKDLYE DVMLENYHNL
60 70 80 90 100
VSVGLACRRP NIIALLEKGK APWMVEPSRK RRGPELGSKD ETKKLPPSQC
110 120 130 140 150
NKSGPSICKK PDSSQQKVPT EKAKHNKNAV PRKNKKGHSG KKSLKCNSCG
160 170 180 190 200
KTFFRSLSLK LHQGFHTGER SYECSTCGQV FRQILSLILH QRVHTQNKSY
210 220 230 240 250
ECDKCGDIFN KKLTLMIHRR SHNGKENFHH EKTSDSCPSL SPHHNNHAID
260 270 280 290 300
SIHQCRKCGK VFSRMSSLLL HKKIHNRKRI QKYSACGRGF KKKPVLVHKR
310 320 330 340 350
ICIGKKTHEN KALIQSLRQR TYQSENPFTC RKCRKSFSRI SALMLHQRAH
360 370 380 390 400
TSGNPYKCDK CQKDFGRLST LILHLRIHSG EKQFKCNKCE KVCNRLSSFI
410 420 430 440 450
QHKKIHKRKK KLIECKECGK MFGGMKNLKV HLNIHSEEKP FKCNKCSKVF
460 470 480 490 500
GRQSFLSEHQ RIHTGEKPYQ CEECGKAFSH RISLTRHKRI HSEDRPYECD
510 520 530 540 550
LCGKAFSQSA HLAQHERIHT GEKPYACKIC KKSFTQRISL ILHERSHTGE
560 570 580 590 600
KPYECNECGK AFSSGSDLIR HQRSHSSEKP YECSKCGKAY SRSSSLIRHQ

SIHSEEMS
Length:608
Mass (Da):70,038
Last modified:February 1, 2005 - v1
Checksum:i99BB8EB373514ED5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY221750 mRNA Translation: AAO67708.1
RefSeqiNP_001008557.1, NM_001008557.1
XP_006228251.1, XM_006228189.3
UniGeneiRn.43493

Genome annotation databases

EnsembliENSRNOT00000063956; ENSRNOP00000061115; ENSRNOG00000033906
GeneIDi308326
KEGGirno:308326
UCSCiRGD:1359114 rat

Similar proteinsi

Entry informationi

Entry nameiZN667_RAT
AccessioniPrimary (citable) accession number: Q5MYW4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: February 1, 2005
Last modified: February 28, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health