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Protein
Submitted name:

1-cys peroxiredoxin

Gene

prx

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • antioxidant activity Source: GeneDB
  • peroxidase activity Source: UniProtKB-KW
  • peroxiredoxin activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, PeroxidaseImported

Enzyme and pathway databases

ReactomeiR-PFA-3299685. Detoxification of Reactive Oxygen Species.
R-PFA-5628897. TP53 Regulates Metabolic Genes.

Names & Taxonomyi

Protein namesi
Submitted name:
1-cys peroxiredoxinImported (EC:1.11.1.15Imported)
Submitted name:
PeroxiredoxinImported
Gene namesi
Name:prxImported
ORF Names:PF3D7_0729200Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0729200.

Subcellular locationi

GO - Cellular componenti

  • apicoplast Source: GeneDB
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500817539821 – 240Sequence analysisAdd BLAST220

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XIYX-ray1.80A/B60-240[»]
4D73X-ray1.80A/B59-238[»]
ProteinModelPortaliQ5MYR6.
SMRiQ5MYR6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini60 – 218RedoxinInterPro annotationAdd BLAST159

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOGENOMiHOG000255884.
PhylomeDBiQ5MYR6.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR013740. Redoxin.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF08534. Redoxin. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5MYR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRMRRTILIF TVILIPLTFC FKNALIKHSI NIVSKRGNSK NRFSQKVYES
60 70 80 90 100
KNIDLENDIK ENDLIPNVKV MIDVRNMNNI SDTDGSPNDF TSIDTHELFN
110 120 130 140 150
NKKILLISLP GAFTPTCSTK MIPGYEEEYD YFIKENNFDD IYCITNNDIY
160 170 180 190 200
VLKSWFKSMD IKKIKYISDG NSSFTESMNM LVDKSNFFMG MRPWRFVAIV
210 220 230 240
ENNILVKMFQ EKDKQHNIQT DPYDISTVNN VKEFLKNNQL
Length:240
Mass (Da):28,124
Last modified:February 1, 2005 - v1
Checksum:iEC5A7A4FCA3D80ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY306209 mRNA. Translation: AAQ76285.1.
AL844506 Genomic DNA. Translation: CAX64072.1.
RefSeqiXP_002808799.1. XM_002808753.1.

Genome annotation databases

EnsemblProtistsiCAX64072; CAX64072; PF3D7_0729200.
MAL7P1.159:mRNA; MAL7P1.159:pep; MAL7P1.159.
GeneDBiPF3D7_0729200.1:pep.
GeneIDi2655035.
KEGGipfa:MAL7P1.159.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY306209 mRNA. Translation: AAQ76285.1.
AL844506 Genomic DNA. Translation: CAX64072.1.
RefSeqiXP_002808799.1. XM_002808753.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XIYX-ray1.80A/B60-240[»]
4D73X-ray1.80A/B59-238[»]
ProteinModelPortaliQ5MYR6.
SMRiQ5MYR6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCAX64072; CAX64072; PF3D7_0729200.
MAL7P1.159:mRNA; MAL7P1.159:pep; MAL7P1.159.
GeneDBiPF3D7_0729200.1:pep.
GeneIDi2655035.
KEGGipfa:MAL7P1.159.

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0729200.

Phylogenomic databases

HOGENOMiHOG000255884.
PhylomeDBiQ5MYR6.

Enzyme and pathway databases

ReactomeiR-PFA-3299685. Detoxification of Reactive Oxygen Species.
R-PFA-5628897. TP53 Regulates Metabolic Genes.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR013740. Redoxin.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF08534. Redoxin. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5MYR6_PLAF7
AccessioniPrimary (citable) accession number: Q5MYR6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 2005
Last sequence update: February 1, 2005
Last modified: November 2, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.