Q5MYR6 (Q5MYR6_PLAF7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
1-cys peroxiredoxin EMBL CAX64072.1

Submitted name:
Peroxiredoxin EMBL AAQ76285.1

Gene names

Name:	prx EMBL AAQ76285.1
Synonyms:	PfAOP EMBL CAX64072.1
ORF Names:	MAL7P1.159 EMBL CAX64072.1

Organism

Plasmodium falciparum (isolate 3D7) EMBL AAQ76285.1

Taxonomic identifier

36329 [NCBI]

Taxonomic lineage

Eukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodium › Plasmodium (Laverania)

Protein attributes

Sequence length	240 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 1XIY Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5MYR6 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: EC5A7A4FCA3D80ED	FASTA	240	28,124
	10 20 30 40 50 60 MRMRRTILIF TVILIPLTFC FKNALIKHSI NIVSKRGNSK NRFSQKVYES KNIDLENDIK 70 80 90 100 110 120 ENDLIPNVKV MIDVRNMNNI SDTDGSPNDF TSIDTHELFN NKKILLISLP GAFTPTCSTK 130 140 150 160 170 180 MIPGYEEEYD YFIKENNFDD IYCITNNDIY VLKSWFKSMD IKKIKYISDG NSSFTESMNM 190 200 210 220 230 240 LVDKSNFFMG MRPWRFVAIV ENNILVKMFQ EKDKQHNIQT DPYDISTVNN VKEFLKNNQL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13." Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D., Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K., Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T., Christodoulou Z. , Clark L., Clark R., Corton C., Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R., Sulston J.E., Craig A., Newbold C., Barrell B.G. Nature 419:527-531(2002) [PubMed: 12368867] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate 3D7.
[2]	"Genome sequence of the human malaria parasite Plasmodium falciparum." Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D., Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S. , Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G. Nature 419:498-511(2002) [PubMed: 12368864] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate 3D7.
[3]	"New peroxiredoxin of the malarial parasite Plasmodium falciparum." Nickel C., Rahlfs S., Becker K. J. Mol. Biol. 0:0-0(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: 3D7 EMBL AAQ76285.1.
[4]	"Crystal structure of a novel Plasmodium falciparum 1-Cys peroxiredoxin." Sarma G.N., Nickel C., Rahlfs S., Fischer M., Becker K., Karplus P.A. J. Mol. Biol. 346:1021-1034(2005) [PubMed: 15701514] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 3D7 EMBL AAQ76285.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AY306209 mRNA. Translation: AAQ76285.1.
AL844506 Genomic DNA. Translation: CAX64072.1.

RefSeq

XP_002808799.1. XM_002808753.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1XIY	X-ray	1.80	A/B	60-240	[»]

ProteinModelPortal

Q5MYR6.

SMR

Q5MYR6. Positions 61-238.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblProtists

MAL7P1.159:mRNA; MAL7P1.159:pep; MAL7P1.159.

GeneID

2655035.

GenomeReviews

Gene locus prx in contig AL844506_GR.

KEGG

pfa:MAL7P1.159.

Phylogenomic databases

GeneTree

EPrGT00050000005561.

HOGENOM

HBG493509.

ProtClustDB

CLSZ2430166.

Family and domain databases

InterPro

IPR013740. Redoxin.
IPR012336. Thioredoxin-like_fold.
[Graphical view]

Gene3D

G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.

Pfam

PF08534. Redoxin. 1 hit.
[Graphical view]

SUPFAM

SSF52833. Thiordxn-like_fd. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q5MYR6_PLAF7

Accession

Primary (citable) accession number: Q5MYR6

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)