Metalloproteinase - Serratia proteamaculans

Preferred order of sections

Names and origin

Protein names

Submitted name:
Metalloproteinase EMBL AAV88082.1

Gene names

Name:

mpr EMBL AAV88082.1

Organism

Serratia proteamaculans EMBL AAV88082.1

Taxonomic identifier

28151 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Serratia

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Metal-binding PDB 2VQX Zinc PDB 2VQX
Technical term	3D-structure PDB 2VQX
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

162

1

Zinc; via tele nitrogen PDB 2VQX

Metal binding

166

1

Zinc; via tele nitrogen PDB 2VQX

Metal binding

186

1

Zinc PDB 2VQX

Sequences

Sequence

Length

Mass (Da)

Tools

Q5MJ80 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 4C6BC906CCBA6DF4
Show »

FASTA

341

37,467

        10         20         30         40         50         60 
MPTLTARSVI PPYMLRRIIE HGSLPQRDCA LHTLNHVQSL LGNKPLRAPG AKTSTGGEVI 

        70         80         90        100        110        120 
RDIYDAENST QLPGKQVRNE GQASNHDVAV DEAYDYLGVT YDFFWQAFKR NSLDNQGLPL 

       130        140        150        160        170        180 
TGSVHYGKEY QNAFWNGQQM VFGDGDGEIF NRFTIAIDVV GHELAHGVTE SEAGLIYFQQ 

       190        200        210        220        230        240 
AGALNESLSD VFGSLVKQFH LKQTADKADW LIGEGLLAKG INGKGLRSMS APGTAYDDPL 

       250        260        270        280        290        300 
LGKDPQPASM KDYIQTKEDN GGVHLNSGIP NRAFYLAATA LGGYAWEKAG YIWYDTLCDK 

       310        320        330        340 
ALPQDADFAT FARTTVKHAE QRFDSKVAQK VQQAWHQVGV A

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References

[1]

"Cloning, sequencing, expression, and characterization of protealysin, a novel neutral proteinase from Serratia proteamaculans representing a new group of thermolysin-like proteases with short N-terminal region of precursor."
Demidyuk I.V., Kalashnikov A.E., Gromova T.Y., Gasanov E.V., Safina D.R., Zabolotskaya M.V., Rudenskaya G.N., Kostrov S.V.
Protein Expr. Purif. 47:551-561(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 94 EMBL AAV88082.1.

[2]

"Crystal structure of the protealysin precursor: insights into propeptide function."
Demidyuk I.V., Gromova T.Y., Polyakov K.M., Melik-Adamyan W.R., Kuranova I.P., Kostrov S.V.
J. Biol. Chem. 285:2003-2013(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.82 ANGSTROMS) IN COMPLEX WITH ZINC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AY819662 Genomic DNA. Translation: AAV88082.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2VQX	X-ray	1.82	A	1-341	[»]

ProteinModelPortal

Q5MJ80.

ModBase

Search...

Protein family/group databases

MEROPS

M04.025.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

3.10.170.10. 1 hit.

InterPro

IPR023612. Peptidase_M4.
IPR001570. Peptidase_M4_C_domain.
IPR013856. Peptidase_M4_domain.
[Graphical view]

Pfam

PF01447. Peptidase_M4. 1 hit.
PF02868. Peptidase_M4_C. 1 hit.
[Graphical view]

PRINTS

PR00730. THERMOLYSIN.

ProtoNet

Search...

Other

EvolutionaryTrace

Q5MJ80.

Entry information

Entry name

Q5MJ80_9ENTR

Accession

Primary (citable) accession number: Q5MJ80

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	March 6, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)