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Q5MJ80

- Q5MJ80_9ENTR

UniProt

Q5MJ80 - Q5MJ80_9ENTR

Protein
Submitted name:

Metalloproteinase

Gene

mpr

Organism
Serratia proteamaculans
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (01 Feb 2005)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi162 – 1621Zinc; via tele nitrogenImported
    Metal bindingi166 – 1661Zinc; via tele nitrogenImported
    Metal bindingi186 – 1861ZincImported

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. metalloendopeptidase activity Source: InterPro

    Keywords - Ligandi

    Metal-bindingImported, ZincImported

    Protein family/group databases

    MEROPSiM04.025.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MetalloproteinaseImported
    Gene namesi
    Name:mprImported
    OrganismiSerratia proteamaculansImported
    Taxonomic identifieri28151 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSerratia

    Interactioni

    Protein-protein interaction databases

    IntActiQ5MJ80. 1 interaction.
    MINTiMINT-8287687.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2VQXX-ray1.82A1-341[»]
    ProteinModelPortaliQ5MJ80.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ5MJ80.

    Family & Domainsi

    Family and domain databases

    Gene3Di3.10.170.10. 1 hit.
    InterProiIPR023612. Peptidase_M4.
    IPR001570. Peptidase_M4_C_domain.
    IPR013856. Peptidase_M4_domain.
    [Graphical view]
    PfamiPF01447. Peptidase_M4. 1 hit.
    PF02868. Peptidase_M4_C. 1 hit.
    [Graphical view]
    PRINTSiPR00730. THERMOLYSIN.

    Sequencei

    Sequence statusi: Complete.

    Q5MJ80-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPTLTARSVI PPYMLRRIIE HGSLPQRDCA LHTLNHVQSL LGNKPLRAPG    50
    AKTSTGGEVI RDIYDAENST QLPGKQVRNE GQASNHDVAV DEAYDYLGVT 100
    YDFFWQAFKR NSLDNQGLPL TGSVHYGKEY QNAFWNGQQM VFGDGDGEIF 150
    NRFTIAIDVV GHELAHGVTE SEAGLIYFQQ AGALNESLSD VFGSLVKQFH 200
    LKQTADKADW LIGEGLLAKG INGKGLRSMS APGTAYDDPL LGKDPQPASM 250
    KDYIQTKEDN GGVHLNSGIP NRAFYLAATA LGGYAWEKAG YIWYDTLCDK 300
    ALPQDADFAT FARTTVKHAE QRFDSKVAQK VQQAWHQVGV A 341
    Length:341
    Mass (Da):37,467
    Last modified:February 1, 2005 - v1
    Checksum:i4C6BC906CCBA6DF4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY819662 Genomic DNA. Translation: AAV88082.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY819662 Genomic DNA. Translation: AAV88082.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2VQX X-ray 1.82 A 1-341 [» ]
    ProteinModelPortali Q5MJ80.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q5MJ80. 1 interaction.
    MINTi MINT-8287687.

    Protein family/group databases

    MEROPSi M04.025.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei Q5MJ80.

    Family and domain databases

    Gene3Di 3.10.170.10. 1 hit.
    InterProi IPR023612. Peptidase_M4.
    IPR001570. Peptidase_M4_C_domain.
    IPR013856. Peptidase_M4_domain.
    [Graphical view ]
    Pfami PF01447. Peptidase_M4. 1 hit.
    PF02868. Peptidase_M4_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00730. THERMOLYSIN.
    ProtoNeti Search...

    Publicationsi

    1. "Cloning, sequencing, expression, and characterization of protealysin, a novel neutral proteinase from Serratia proteamaculans representing a new group of thermolysin-like proteases with short N-terminal region of precursor."
      Demidyuk I.V., Kalashnikov A.E., Gromova T.Y., Gasanov E.V., Safina D.R., Zabolotskaya M.V., Rudenskaya G.N., Kostrov S.V.
      Protein Expr. Purif. 47:551-561(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 94Imported.
    2. "Crystal structure of the protealysin precursor: insights into propeptide function."
      Demidyuk I.V., Gromova T.Y., Polyakov K.M., Melik-Adamyan W.R., Kuranova I.P., Kostrov S.V.
      J. Biol. Chem. 285:2003-2013(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.82 ANGSTROMS) IN COMPLEX WITH ZINC.

    Entry informationi

    Entry nameiQ5MJ80_9ENTR
    AccessioniPrimary (citable) accession number: Q5MJ80
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 1, 2005
    Last sequence update: February 1, 2005
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3