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Protein

Sperm protein associated with the nucleus on the X chromosome N3

Gene

SPANXN3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Sperm protein associated with the nucleus on the X chromosome N3
Alternative name(s):
Nuclear-associated protein SPAN-Xn3
Short name:
SPANX-N3
SPANX family member N3
Gene namesi
Name:SPANXN3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000189252.4.
HGNCiHGNC:33176. SPANXN3.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162404385.

Polymorphism and mutation databases

BioMutaiSPANXN3.
DMDMi74743051.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002855401 – 141Sperm protein associated with the nucleus on the X chromosome N3Add BLAST141

Proteomic databases

EPDiQ5MJ09.
PaxDbiQ5MJ09.
PeptideAtlasiQ5MJ09.
PRIDEiQ5MJ09.

PTM databases

iPTMnetiQ5MJ09.
PhosphoSitePlusiQ5MJ09.

Expressioni

Gene expression databases

BgeeiENSG00000189252.
CleanExiHS_SPANXN3.

Organism-specific databases

HPAiHPA045652.

Interactioni

Protein-protein interaction databases

BioGridi126541. 11 interactors.
IntActiQ5MJ09. 9 interactors.
STRINGi9606.ENSP00000359534.

Structurei

3D structure databases

ProteinModelPortaliQ5MJ09.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SPAN-X family.Curated

Phylogenomic databases

eggNOGiENOG410JMMV. Eukaryota.
ENOG41115AG. LUCA.
HOGENOMiHOG000015252.
HOVERGENiHBG097736.
InParanoidiQ5MJ09.
OrthoDBiEOG091G0PSU.
PhylomeDBiQ5MJ09.
TreeFamiTF341404.

Family and domain databases

InterProiView protein in InterPro
IPR010007. SPAN-X_fam.
PANTHERiPTHR23425. PTHR23425. 1 hit.
PfamiView protein in Pfam
PF07458. SPAN-X. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5MJ09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQPTSSTNG EKTKSPCESN NKKNDEMQEV PNRVLAPEQS LKKTKTSEYP
60 70 80 90 100
IIFVYYLRKG KKINSNQLEN EQSQENSINP IQKEEDEGVD LSEGSSNEDE
110 120 130 140
DLGPCEGPSK EDKDLDSSEG SSQEDEDLGL SEGSSQDSGE D
Length:141
Mass (Da):15,595
Last modified:February 1, 2005 - v1
Checksum:i036B1450B93000C4
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03202643K → N1 PublicationCorresponds to variant dbSNP:rs6654212Ensembl.1
Natural variantiVAR_05368489V → I. Corresponds to variant dbSNP:rs5953851Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY825031 Genomic DNA. Translation: AAV97587.1.
DQ336128 mRNA. Translation: ABC61879.1.
DQ336129 mRNA. Translation: ABC61880.1.
AL030997, AL080239 Genomic DNA. Translation: CAI42274.1.
AL080239, AL030997 Genomic DNA. Translation: CAI41648.1.
BC062750 mRNA. Translation: AAH62750.1.
CCDSiCCDS35418.1.
RefSeqiNP_001009609.2. NM_001009609.3.
UniGeneiHs.447320.

Genome annotation databases

EnsembliENST00000370503; ENSP00000359534; ENSG00000189252.
GeneIDi139067.
KEGGihsa:139067.
UCSCiuc004fbw.4. human.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiSPXN3_HUMAN
AccessioniPrimary (citable) accession number: Q5MJ09
Secondary accession number(s): Q0ZNK4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: February 1, 2005
Last modified: September 27, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families