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Protein

Protein TBRG4

Gene

Tbrg4

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in cell cycle progression.By similarity

GO - Molecular functioni

GO - Biological processi

  • cellular respiration Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein TBRG4
Alternative name(s):
Transforming growth factor beta regulator 4
Gene namesi
Name:Tbrg4
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 14

Organism-specific databases

RGDi1309737. Tbrg4.

Subcellular locationi

  • Mitochondrion By similarity

GO - Cellular componenti

  • mitochondrion Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000273029? – 629Protein TBRG4
Transit peptidei1 – ?MitochondrionCurated

Proteomic databases

PaxDbiQ5M9G9.
PRIDEiQ5M9G9.

PTM databases

iPTMnetiQ5M9G9.
PhosphoSitePlusiQ5M9G9.

Expressioni

Gene expression databases

BgeeiENSRNOG00000037664.
GenevisibleiQ5M9G9. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000053972.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini559 – 617RAPPROSITE-ProRule annotationAdd BLAST59

Sequence similaritiesi

Belongs to the FAST kinase family.Curated
Contains 1 RAP domain.PROSITE-ProRule annotation

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410IEJA. Eukaryota.
ENOG4111EYX. LUCA.
GeneTreeiENSGT00530000063266.
HOGENOMiHOG000253019.
HOVERGENiHBG094028.
InParanoidiQ5M9G9.
OMAiKVGHLSE.
OrthoDBiEOG091G0WV6.
PhylomeDBiQ5M9G9.
TreeFamiTF324885.

Family and domain databases

InterProiIPR013579. FAST_2.
IPR010622. FAST_Leu-rich.
IPR013584. RAP.
[Graphical view]
PfamiPF06743. FAST_1. 1 hit.
PF08368. FAST_2. 1 hit.
PF08373. RAP. 1 hit.
[Graphical view]
SMARTiSM00952. RAP. 1 hit.
[Graphical view]
PROSITEiPS51286. RAP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5M9G9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVRLMKQCT CLLREATRLV PTVAPVGRLR LAGVACKTLT SSVSSPSSGS
60 70 80 90 100
LTELLGKEQV FTPYPEHQEV DYLIEKATRP EELLELLGGD HSLHHNHAAL
110 120 130 140 150
ILIRLSYLLS EKPKEKALLV EDARFQQLVR LVDSQITSVW HGTLVKLLRS
160 170 180 190 200
LYTLVLPQGS KELRSVEQEV RWRLRRLKYK HLVFLAESCA PFMKEQHSKE
210 220 230 240 250
LLAELLRHLE RRWTEISDSR TLVSMMTMAG HLSESLMNRL EDKCLELVEQ
260 270 280 290 300
FGPDELRKVL MTLAAQSRRS VPLLRAISYH LVQKPFPMTK GMLLDLAYAY
310 320 330 340 350
GKLSFHQTQV AQRLAADLLP FIPSMTPGEV ARCAKSFAFL KWLNLPLFEA
360 370 380 390 400
FTQHLLNSAQ DVSLSHLCSV LLAFARLNFH PEQEDQFFNL VHEKLDSVLG
410 420 430 440 450
SLEPALQVDL VWALCVLQQV QVAELQTVLH PGLHTRFLES KSPKDQSTFQ
460 470 480 490 500
KLVHINSTAL LEYPEYKGPF LPASAVAPSP SPSNKKMTPL QKELQDALKA
510 520 530 540 550
LLGNNDTGSL EVATQYGWVL DAEVLLDAEG HFLPLRDFVA PHLAQPVGNQ
560 570 580 590 600
PLPPGAKRIA FLRWEFPNFN SRSKDLLGRF VLARRHVLAA GFLVVDVPYY
610 620
EWLDLKSEWQ KTAYLKDKMR KAVAEELAK
Length:629
Mass (Da):71,181
Last modified:February 1, 2005 - v1
Checksum:iBE6CA495C747BC6E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087073 mRNA. Translation: AAH87073.1.
RefSeqiNP_001012154.1. NM_001012154.1.
XP_006251404.1. XM_006251342.3.
XP_006251405.1. XM_006251343.3.
UniGeneiRn.22830.

Genome annotation databases

EnsembliENSRNOT00000089133; ENSRNOP00000074223; ENSRNOG00000052477.
GeneIDi360977.
KEGGirno:360977.
UCSCiRGD:1309737. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087073 mRNA. Translation: AAH87073.1.
RefSeqiNP_001012154.1. NM_001012154.1.
XP_006251404.1. XM_006251342.3.
XP_006251405.1. XM_006251343.3.
UniGeneiRn.22830.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000053972.

PTM databases

iPTMnetiQ5M9G9.
PhosphoSitePlusiQ5M9G9.

Proteomic databases

PaxDbiQ5M9G9.
PRIDEiQ5M9G9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000089133; ENSRNOP00000074223; ENSRNOG00000052477.
GeneIDi360977.
KEGGirno:360977.
UCSCiRGD:1309737. rat.

Organism-specific databases

CTDi9238.
RGDi1309737. Tbrg4.

Phylogenomic databases

eggNOGiENOG410IEJA. Eukaryota.
ENOG4111EYX. LUCA.
GeneTreeiENSGT00530000063266.
HOGENOMiHOG000253019.
HOVERGENiHBG094028.
InParanoidiQ5M9G9.
OMAiKVGHLSE.
OrthoDBiEOG091G0WV6.
PhylomeDBiQ5M9G9.
TreeFamiTF324885.

Miscellaneous databases

PROiQ5M9G9.

Gene expression databases

BgeeiENSRNOG00000037664.
GenevisibleiQ5M9G9. RN.

Family and domain databases

InterProiIPR013579. FAST_2.
IPR010622. FAST_Leu-rich.
IPR013584. RAP.
[Graphical view]
PfamiPF06743. FAST_1. 1 hit.
PF08368. FAST_2. 1 hit.
PF08373. RAP. 1 hit.
[Graphical view]
SMARTiSM00952. RAP. 1 hit.
[Graphical view]
PROSITEiPS51286. RAP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTBRG4_RAT
AccessioniPrimary (citable) accession number: Q5M9G9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: February 1, 2005
Last modified: November 2, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.