ID   Q5M976_XENTR            Unreviewed;       243 AA.
AC   Q5M976;
DT   01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   01-FEB-2005, sequence version 1.
DT   27-MAR-2024, entry version 99.
DE   SubName: Full=Hypothetical LOC496623 {ECO:0000313|EMBL:AAH87563.1};
GN   Name=LOC496623 {ECO:0000313|EMBL:AAH87563.1,
GN   ECO:0000313|RefSeq:NP_001011199.1,
GN   ECO:0000313|Xenbase:XB-GENE-29098963};
GN   ORFNames=XENTR_v90029055mg {ECO:0000313|EMBL:OCA15854.1};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364 {ECO:0000313|EMBL:AAH87563.1};
RN   [1] {ECO:0000313|RefSeq:NP_001011199.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=12454917; DOI=10.1002/dvdy.10174;
RA   Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA   Richardson P.;
RT   "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT   initiative.";
RL   Dev. Dyn. 225:384-391(2002).
RN   [2] {ECO:0000313|EMBL:AAH87563.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo {ECO:0000313|EMBL:AAH87563.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:OCA15854.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Nigerian {ECO:0000313|EMBL:OCA15854.1};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Ottilar R., Schmutz J., Salamov A., Cheng J.F., Lucas S., Pitluck S.,
RA   Gundlach H., Guo Y., Haberer G., Nasrallah J., Mayer K.F.X.,
RA   van de Peer Y., Weigel D., Grigoriev I.V.;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:OCA15854.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nigerian {ECO:0000313|EMBL:OCA15854.1};
RX   PubMed=20431018; DOI=10.1126/science.1183670;
RA   Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA   Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA   Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA   Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA   Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA   Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA   Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA   Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA   Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT   "The genome of the Western clawed frog Xenopus tropicalis.";
RL   Science 328:633-636(2010).
RN   [5] {ECO:0000313|EMBL:OCA15854.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Nigerian {ECO:0000313|EMBL:OCA15854.1};
RA   Sessions A., Jenkins J., Mitros T., Lyons J.T., Dichmann D.S., Robert J.,
RA   Harland R.M., Rokhsar D.S.;
RT   "WGS assembly of Xenopus tropicalis.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|RefSeq:NP_001011199.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; BC087563; AAH87563.1; -; mRNA.
DR   EMBL; KV460722; OCA15854.1; -; Genomic_DNA.
DR   RefSeq; NP_001011199.1; NM_001011199.2.
DR   RefSeq; XP_017945756.1; XM_018090267.1.
DR   MEROPS; S01.126; -.
DR   DNASU; 496623; -.
DR   GeneID; 496623; -.
DR   KEGG; xtr:496623; -.
DR   Xenbase; XB-GENE-29098963; LOC496623.
DR   OrthoDB; 4629979at2759; -.
DR   Proteomes; UP000008143; Chromosome 7.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0007586; P:digestion; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00190; Tryp_SPc; 1.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001314; Peptidase_S1A.
DR   InterPro; IPR001254; Trypsin_dom.
DR   InterPro; IPR018114; TRYPSIN_HIS.
DR   InterPro; IPR033116; TRYPSIN_SER.
DR   PANTHER; PTHR24264:SF15; RIKEN CDNA 2210010C04 GENE; 1.
DR   PANTHER; PTHR24264; TRYPSIN-RELATED; 1.
DR   Pfam; PF00089; Trypsin; 1.
DR   PRINTS; PR00722; CHYMOTRYPSIN.
DR   SMART; SM00020; Tryp_SPc; 1.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR   PROSITE; PS50240; TRYPSIN_DOM; 1.
DR   PROSITE; PS00134; TRYPSIN_HIS; 1.
DR   PROSITE; PS00135; TRYPSIN_SER; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU363034};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU363034};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW   ECO:0000256|RuleBase:RU363034};
KW   Signal {ECO:0000256|SAM:SignalP, ECO:0000313|RefSeq:NP_001011199.1}.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           16..243
FT                   /evidence="ECO:0000256|SAM:SignalP,
FT                   ECO:0000313|RefSeq:NP_001011199.1"
FT                   /id="PRO_5033206085"
FT   DOMAIN          21..241
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
SQ   SEQUENCE   243 AA;  25487 MW;  D0532765E3D79F71 CRC64;
     MKLFLLCVLL GAAAAFDDDK IIGGATCAKN SVPYIVSLNS GYHFCGGSLI NNQWVVSAAH
     CYKASIQVRL GEHNIALSEG TEQFISSSKV IRHSGYNSWT LDNDIMLIKL SSAASLNAAV
     NAVALPSGCA AAGASCLISG WGNTLSSGSN YPDLLQCLYA PILTDAQCNN AYPGEITNNM
     ICLGFLEGGK DSCQGDSGGP VVCNGELQGV VSWGYGCAQR NYPGVYTKVC NYNSWIQSTI
     AAN
//