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Protein
Submitted name:

Ataxin-3

Gene

Atxn3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei14PROSITE-ProRule annotation1
Active sitei119PROSITE-ProRule annotation1
Active sitei134PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolasePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ataxin-3Imported
Submitted name:
Atxn3 proteinImported
Gene namesi
Name:Atxn3Imported
Synonyms:MjdImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1099442. Atxn3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000021189.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 180JosephinInterPro annotationAdd BLAST180

Phylogenomic databases

eggNOGiKOG2935. Eukaryota.
ENOG4111G4B. LUCA.
GeneTreeiENSGT00390000001830.
HOGENOMiHOG000006034.
HOVERGENiHBG025648.

Family and domain databases

InterProiView protein in InterPro
IPR033865. Ataxin-3.
IPR006155. Josephin.
IPR003903. UIM_dom.
PANTHERiPTHR14159. PTHR14159. 1 hit.
PfamiView protein in Pfam
PF02099. Josephin. 1 hit.
PF02809. UIM. 2 hits.
SMARTiView protein in SMART
SM01246. Josephin. 1 hit.
SM00726. UIM. 2 hits.
PROSITEiView protein in PROSITE
PS50957. JOSEPHIN. 1 hit.
PS50330. UIM. 2 hits.

Sequencei

Sequence statusi: Complete.

Q5M8S1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESIFHEKQE GSLCAQHCLN NLLQGEYFSP VELSSIAHQL DEEERLRMAE
60 70 80 90 100
GGVTSEDYRT FLQQPSGNMD DSGFFSIQVI SNALKVWGLE LILFNSPEYQ
110 120 130 140 150
RLRIDPINER SFICNYKEHW FTVRKLGKQW FNLNSLLTGP ELISDTYLAL
160 170 180 190 200
FLAQLQQEGY SIFVVKGDLP DCEADQLLQM IKVQQMHRPK LIGEELAHLK
210 220 230 240 250
EQSALKADLE RVLEAADGSG IFDEDEDDLQ RALAISRQEI DMEDEEADLR
260 270 280 290
RAIQLSMQVP EVCVKIVHRH QVQISLQKSC GGDEKPTLKS KVVGTD
Length:296
Mass (Da):33,757
Last modified:February 1, 2005 - v1
Checksum:iE10F4A3719B7EB85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121965 Genomic DNA. No translation available.
BC087880 mRNA. Translation: AAH87880.1.
RefSeqiNP_001161386.1. NM_001167914.1.
UniGeneiMm.271914.

Genome annotation databases

EnsembliENSMUST00000160251; ENSMUSP00000125082; ENSMUSG00000021189.
GeneIDi110616.
UCSCiuc011yql.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ5M8S1_MOUSE
AccessioniPrimary (citable) accession number: Q5M8S1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 2005
Last sequence update: February 1, 2005
Last modified: August 30, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported