Q5M8H5 (MOGT2_XENTR) Reviewed, UniProtKB/Swiss-Prot
Last modified
November 16, 2011.
Version 48.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: 2-acylglycerol O-acyltransferase 2 EC=2.3.1.22 Alternative name(s): Acyl-CoA:monoacylglycerol acyltransferase 2 Short name=MGAT2 Monoacylglycerol O-acyltransferase 2 | ||
| Gene names |
| ||
| Organism | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | ||
| Taxonomic identifier | 8364 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana |
Protein attributes
| Sequence length | 335 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA By similarity. |
| Catalytic activity | Acyl-CoA + 2-acylglycerol = CoA + diacylglycerol. |
| Pathway | |
| Subcellular location | Endoplasmic reticulum membrane; Multi-pass membrane protein By similarity. |
| Sequence similarities | Belongs to the diacylglycerol acyltransferase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Glycerol metabolism Lipid metabolism Lipid synthesis |
| Cellular component | Endoplasmic reticulum Membrane |
| Domain | Transmembrane Transmembrane helix |
| Molecular function | Acyltransferase Transferase |
| PTM | Glycoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | glycerol metabolic process Inferred from electronic annotation. Source: UniProtKB-KW lipid biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | endoplasmic reticulum membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membraneInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | 2-acylglycerol O-acyltransferase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 335 | 335 | 2-acylglycerol O-acyltransferase 2 | PRO_0000249066 | |||||
Regions | |||||||||
| Transmembrane | 24 – 44 | 21 | Helical; Potential | ||||||
| Transmembrane | 104 – 124 | 21 | Helical; Potential | ||||||
Amino acid modifications | |||||||||
| Glycosylation | 206 | 1 | N-linked (GlcNAc...) Potential | ||||||
Sequences
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References
| [1] | NIH - Xenopus Gene Collection (XGC) project Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BC088019 mRNA. Translation: AAH88019.1. |
| RefSeq | NP_001011301.1. NM_001011301.1. |
| UniGene | Str.27777. |
3D structure databases | |
| ProteinModelPortal | Q5M8H5. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| Ensembl | ENSXETT00000008697; ENSXETP00000008697; ENSXETG00000004012. |
| GeneID | 496754. |
| KEGG | xtr:496754. |
Organism-specific databases | |
| CTD | 496214. |
| Xenbase | XB-GENE-6040330. mogat2.1. |
Phylogenomic databases | |
| eggNOG | veNOG04599. |
| GeneTree | ENSGT00550000074276. |
| HOGENOM | HBG561030. |
| HOVERGEN | HBG065791. |
| InParanoid | Q5M8H5. |
| OMA | VENHENN. |
| OrthoDB | EOG4BP1C4. |
Gene expression databases | |
| Bgee | Q5M8H5. |
Family and domain databases | |
| InterPro | IPR007130. DAGAT. [Graphical view] |
| KO | K14457. |
| PANTHER | PTHR12317. DAGAT. 1 hit. |
| Pfam | PF03982. DAGAT. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | MOGT2_XENTR | ||||||||
| Accession | Primary (citable) accession number: Q5M8H5 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with