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Q5M882

- RPP29_RAT

UniProt

Q5M882 - RPP29_RAT

Protein

Ribonuclease P protein subunit p29

Gene

Pop4

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (01 Feb 2005)
      Previous versions | rss
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    Functioni

    Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P By similarity.By similarity

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-EC
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. mRNA cleavage Source: InterPro
    2. rRNA processing Source: InterPro
    3. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    tRNA processing

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein subunit p29 (EC:3.1.26.5)
    Gene namesi
    Name:Pop4
    Synonyms:Rpp29
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 1

    Organism-specific databases

    RGDi1305955. Pop4.

    Subcellular locationi

    Nucleusnucleolus By similarity

    GO - Cellular componenti

    1. nucleolar ribonuclease P complex Source: InterPro
    2. ribonuclease MRP complex Source: InterPro

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 221221Ribonuclease P protein subunit p29PRO_0000128421Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei10 – 101PhosphoserineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiQ5M882.

    Expressioni

    Gene expression databases

    GenevestigatoriQ5M882.

    Interactioni

    Subunit structurei

    Component of nuclear RNase P and RNase MRP ribonucleoproteins. RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of an RNA moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40, POP5 and RPP21. Interacts with RPP25 and POP5 By similarity.By similarity

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000020474.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5M882.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiNOG255667.
    GeneTreeiENSGT00390000010067.
    HOGENOMiHOG000007746.
    HOVERGENiHBG002676.
    InParanoidiQ5M882.
    KOiK03538.
    OMAiMSQQACE.
    OrthoDBiEOG786H4B.
    PhylomeDBiQ5M882.
    TreeFamiTF313883.

    Family and domain databases

    Gene3Di2.30.30.210. 1 hit.
    InterProiIPR002730. RNase_P/MRP_p29.
    IPR016848. RNase_P/MRP_p29-subunit.
    IPR023534. Rof/RNase_P-like.
    [Graphical view]
    PfamiPF01868. UPF0086. 1 hit.
    [Graphical view]
    PIRSFiPIRSF027081. RNase_P/MRP_p29_subunit. 1 hit.
    SMARTiSM00538. POP4. 1 hit.
    [Graphical view]
    SUPFAMiSSF101744. SSF101744. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5M882-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKAVIYHAFS HKEAKDHDVQ ELGTQRAEAF VRAFLKQSIP HMSQQDCESH    50
    LQRKAVILEY FTRLKPKPRP KKKSKGLSAK QRRELRLFDI KPEQQRYSLF 100
    LPLHELWKQY IRDLCNGLKP DTQPQMIQAK LLKADLHGAV ISVTKSKCPS 150
    YVGVTGILLQ ETKHVFKIIT KEDHLKVIPK QNCVFTIEID DFISYIYGSK 200
    FQLRASERSA KKFKAKGTID L 221
    Length:221
    Mass (Da):25,633
    Last modified:February 1, 2005 - v1
    Checksum:i1BC37779DD9B099E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC088183 mRNA. Translation: AAH88183.1.
    RefSeqiNP_001009642.1. NM_001009642.1.
    UniGeneiRn.3013.

    Genome annotation databases

    EnsembliENSRNOT00000020474; ENSRNOP00000020474; ENSRNOG00000027646.
    GeneIDi292831.
    KEGGirno:292831.
    UCSCiRGD:1305955. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC088183 mRNA. Translation: AAH88183.1 .
    RefSeqi NP_001009642.1. NM_001009642.1.
    UniGenei Rn.3013.

    3D structure databases

    ProteinModelPortali Q5M882.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000020474.

    Proteomic databases

    PaxDbi Q5M882.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000020474 ; ENSRNOP00000020474 ; ENSRNOG00000027646 .
    GeneIDi 292831.
    KEGGi rno:292831.
    UCSCi RGD:1305955. rat.

    Organism-specific databases

    CTDi 10775.
    RGDi 1305955. Pop4.

    Phylogenomic databases

    eggNOGi NOG255667.
    GeneTreei ENSGT00390000010067.
    HOGENOMi HOG000007746.
    HOVERGENi HBG002676.
    InParanoidi Q5M882.
    KOi K03538.
    OMAi MSQQACE.
    OrthoDBi EOG786H4B.
    PhylomeDBi Q5M882.
    TreeFami TF313883.

    Miscellaneous databases

    NextBioi 634875.
    PROi Q5M882.

    Gene expression databases

    Genevestigatori Q5M882.

    Family and domain databases

    Gene3Di 2.30.30.210. 1 hit.
    InterProi IPR002730. RNase_P/MRP_p29.
    IPR016848. RNase_P/MRP_p29-subunit.
    IPR023534. Rof/RNase_P-like.
    [Graphical view ]
    Pfami PF01868. UPF0086. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF027081. RNase_P/MRP_p29_subunit. 1 hit.
    SMARTi SM00538. POP4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF101744. SSF101744. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Spleen.

    Entry informationi

    Entry nameiRPP29_RAT
    AccessioniPrimary (citable) accession number: Q5M882
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2005
    Last sequence update: February 1, 2005
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3