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Q5M882

- RPP29_RAT

UniProt

Q5M882 - RPP29_RAT

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Protein

Ribonuclease P protein subunit p29

Gene

Pop4

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P (By similarity).By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
  2. ribonuclease P RNA binding Source: RefGenome

GO - Biological processi

  1. mRNA cleavage Source: InterPro
  2. RNA phosphodiester bond hydrolysis Source: GOC
  3. RNA phosphodiester bond hydrolysis, endonucleolytic Source: GOC
  4. rRNA processing Source: RefGenome
  5. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit p29 (EC:3.1.26.5)
Gene namesi
Name:Pop4
Synonyms:Rpp29
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 1

Organism-specific databases

RGDi1305955. Pop4.

Subcellular locationi

Nucleusnucleolus By similarity

GO - Cellular componenti

  1. nucleolar ribonuclease P complex Source: InterPro
  2. ribonuclease MRP complex Source: RefGenome
  3. ribonuclease P complex Source: RefGenome
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 221221Ribonuclease P protein subunit p29PRO_0000128421Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei10 – 101PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5M882.

Expressioni

Gene expression databases

GenevestigatoriQ5M882.

Interactioni

Subunit structurei

Component of nuclear RNase P and RNase MRP ribonucleoproteins. RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of an RNA moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40, POP5 and RPP21. Interacts with RPP25 and POP5 (By similarity).By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000020474.

Structurei

3D structure databases

ProteinModelPortaliQ5M882.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG255667.
GeneTreeiENSGT00390000010067.
HOGENOMiHOG000007746.
HOVERGENiHBG002676.
InParanoidiQ5M882.
KOiK03538.
OMAiMSQQACE.
OrthoDBiEOG786H4B.
PhylomeDBiQ5M882.
TreeFamiTF313883.

Family and domain databases

Gene3Di2.30.30.210. 1 hit.
InterProiIPR002730. RNase_P/MRP_p29.
IPR016848. RNase_P/MRP_p29-subunit.
IPR023534. Rof/RNase_P-like.
[Graphical view]
PfamiPF01868. UPF0086. 1 hit.
[Graphical view]
PIRSFiPIRSF027081. RNase_P/MRP_p29_subunit. 1 hit.
SMARTiSM00538. POP4. 1 hit.
[Graphical view]
SUPFAMiSSF101744. SSF101744. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5M882-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKAVIYHAFS HKEAKDHDVQ ELGTQRAEAF VRAFLKQSIP HMSQQDCESH
60 70 80 90 100
LQRKAVILEY FTRLKPKPRP KKKSKGLSAK QRRELRLFDI KPEQQRYSLF
110 120 130 140 150
LPLHELWKQY IRDLCNGLKP DTQPQMIQAK LLKADLHGAV ISVTKSKCPS
160 170 180 190 200
YVGVTGILLQ ETKHVFKIIT KEDHLKVIPK QNCVFTIEID DFISYIYGSK
210 220
FQLRASERSA KKFKAKGTID L
Length:221
Mass (Da):25,633
Last modified:February 1, 2005 - v1
Checksum:i1BC37779DD9B099E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088183 mRNA. Translation: AAH88183.1.
RefSeqiNP_001009642.1. NM_001009642.1.
UniGeneiRn.3013.

Genome annotation databases

EnsembliENSRNOT00000020474; ENSRNOP00000020474; ENSRNOG00000027646.
GeneIDi292831.
KEGGirno:292831.
UCSCiRGD:1305955. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088183 mRNA. Translation: AAH88183.1 .
RefSeqi NP_001009642.1. NM_001009642.1.
UniGenei Rn.3013.

3D structure databases

ProteinModelPortali Q5M882.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000020474.

Proteomic databases

PaxDbi Q5M882.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000020474 ; ENSRNOP00000020474 ; ENSRNOG00000027646 .
GeneIDi 292831.
KEGGi rno:292831.
UCSCi RGD:1305955. rat.

Organism-specific databases

CTDi 10775.
RGDi 1305955. Pop4.

Phylogenomic databases

eggNOGi NOG255667.
GeneTreei ENSGT00390000010067.
HOGENOMi HOG000007746.
HOVERGENi HBG002676.
InParanoidi Q5M882.
KOi K03538.
OMAi MSQQACE.
OrthoDBi EOG786H4B.
PhylomeDBi Q5M882.
TreeFami TF313883.

Miscellaneous databases

NextBioi 634875.
PROi Q5M882.

Gene expression databases

Genevestigatori Q5M882.

Family and domain databases

Gene3Di 2.30.30.210. 1 hit.
InterProi IPR002730. RNase_P/MRP_p29.
IPR016848. RNase_P/MRP_p29-subunit.
IPR023534. Rof/RNase_P-like.
[Graphical view ]
Pfami PF01868. UPF0086. 1 hit.
[Graphical view ]
PIRSFi PIRSF027081. RNase_P/MRP_p29_subunit. 1 hit.
SMARTi SM00538. POP4. 1 hit.
[Graphical view ]
SUPFAMi SSF101744. SSF101744. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Spleen.

Entry informationi

Entry nameiRPP29_RAT
AccessioniPrimary (citable) accession number: Q5M882
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: February 1, 2005
Last modified: October 29, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3