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Protein

MORF4 family-associated protein 1

Gene

Mrfap1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
MORF4 family-associated protein 1
Alternative name(s):
T-cell activation protein-related protein
Gene namesi
Name:Mrfap1Imported
Synonyms:Pgr1Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 14

Organism-specific databases

RGDi628631. Mrfap1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003061791 – 125MORF4 family-associated protein 1Add BLAST125

Proteomic databases

PaxDbiQ5M820.
PRIDEiQ5M820.

PTM databases

PhosphoSitePlusiQ5M820.

Expressioni

Gene expression databases

BgeeiENSRNOG00000055319.
GenevisibleiQ5M820. RN.

Interactioni

Subunit structurei

Found in a complex composed of MORF4L1, MRFAP1 and RB1. Interacts via its N-terminus with MORF4L1. Interacts with CSTB and MORF4L2.By similarity1 Publication

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000008121.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili94 – 124Sequence analysisAdd BLAST31

Sequence similaritiesi

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410J03M. Eukaryota.
ENOG4111AYE. LUCA.
GeneTreeiENSGT00510000046304.
HOGENOMiHOG000070216.
HOVERGENiHBG104090.
InParanoidiQ5M820.

Family and domain databases

InterProiView protein in InterPro
IPR029254. MRFAP1.
PfamiView protein in Pfam
PF15155. MRFAP1. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 11 Publication (identifier: Q5M820-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MRPLDAVELA EPEEVEVLEP EEDFEQFLLP VIHEMREDIA SLTRERGRAP
60 70 80 90 100
VRNRGKLWEM DNMLIQIKTQ VEASEESALN HLQGAGGAEP RGPRAEKADE
110 120
KAQEMAKMAE MLVQLVRRIE KSESS
Note: No experimental confirmation available.Curated
Length:125
Mass (Da):14,222
Last modified:February 1, 2005 - v1
Checksum:i7933F06246BD6085
GO
Isoform 21 Publication (identifier: Q5M820-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     18-41: Missing.

Show »
Length:101
Mass (Da):11,353
Checksum:i822A143636440814
GO

Sequence cautioni

Q5M820: The sequence AAN03958 differs from that shown. Reason: Erroneous initiation.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_05254918 – 41Missing in isoform 2. 1 PublicationAdd BLAST24

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF526268 mRNA. Translation: AAN03958.1. Different initiation.
BC088308 mRNA. Translation: AAH88308.1.
RefSeqiNP_001009264.1. NM_001009264.1. [Q5M820-1]
UniGeneiRn.3393.

Genome annotation databases

EnsembliENSRNOT00000089759; ENSRNOP00000071505; ENSRNOG00000055319. [Q5M820-1]
GeneIDi282585.
KEGGirno:282585.

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiMOFA1_RAT
AccessioniPrimary (citable) accession number: Q5M820
Secondary accession number(s): Q8K3W6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: February 1, 2005
Last modified: October 25, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families