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Protein

Protein canopy homolog 1

Gene

cnpy1

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Plays an role in early embryonic development.By similarity

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein

Names & Taxonomyi

Protein namesi
Recommended name:
Protein canopy homolog 1
Gene namesi
Name:cnpy1
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-981810. cnpy1.

Subcellular locationi

  • Endoplasmic reticulum PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000031401422 – 181Protein canopy homolog 1Add BLAST160

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi29 ↔ 173By similarity
Disulfide bondi32 ↔ 166By similarity
Disulfide bondi87 ↔ 139By similarity

Keywords - PTMi

Disulfide bond

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 177Saposin B-typeAdd BLAST153

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi178 – 181Prevents secretion from ERPROSITE-ProRule annotation4

Sequence similaritiesi

Belongs to the canopy family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOVERGENiHBG052514.

Family and domain databases

InterProiView protein in InterPro
IPR021852. DUF3456.
PfamiView protein in Pfam
PF11938. DUF3456. 1 hit.
PROSITEiView protein in PROSITE
PS00014. ER_TARGET. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5M7D4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAILLHFGVL ITAFLSSHVE GKRDPILYCG ACRALVDELL YEIRKVNPKK
60 70 80 90 100
TVDVGSFRIS PDGKQEQNKV PFAKSELYLT DVLEEICEKM NDYGLYVDPT
110 120 130 140 150
TQEKSYKRFA PRDNEGIGSV DFKNFQFNPE ESNSLKYACE RVVEEHEDEV
160 170 180
LSVITKENDN LADKLCTEET GLCKEYLHNE L
Length:181
Mass (Da):20,706
Last modified:February 1, 2005 - v1
Checksum:iB2B8641C5413F924
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC088697 mRNA. Translation: AAH88697.1.
RefSeqiNP_001088889.1. NM_001095420.1.
UniGeneiXl.87539.

Genome annotation databases

GeneIDi496234.
KEGGixla:496234.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiCNPY1_XENLA
AccessioniPrimary (citable) accession number: Q5M7D4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 1, 2005
Last modified: May 10, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families