Q5M7D4 (CNPY1_XENLA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein canopy homolog 1

Gene names

Name:

cnpy1

Organism

Xenopus laevis (African clawed frog)

Taxonomic identifier

8355 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	181 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Plays an role in early embryonic development By similarity.
Subcellular location	Endoplasmic reticulum By similarity.
Sequence similarities	Belongs to the canopy family. Contains 1 saposin B-type domain.

Ontologies

Keywords
Cellular component	Endoplasmic reticulum
Domain	Signal
Molecular function	Developmental protein
PTM	Disulfide bond
Gene Ontology (GO)
Biological_process	multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	endoplasmic reticulum Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Potential
	Chain	22 – 181	160	Protein canopy homolog 1		PRO_0000314014
Regions
	Domain	25 – 177	153	Saposin B-type
	Motif	178 – 181	4	Prevents secretion from ER Potential
Amino acid modifications
	Disulfide bond	29 ↔ 173		By similarity
	Disulfide bond	32 ↔ 166		By similarity
	Disulfide bond	87 ↔ 139		By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5M7D4 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: B2B8641C5413F924	FASTA	181	20,706
	10 20 30 40 50 60 MAILLHFGVL ITAFLSSHVE GKRDPILYCG ACRALVDELL YEIRKVNPKK TVDVGSFRIS 70 80 90 100 110 120 PDGKQEQNKV PFAKSELYLT DVLEEICEKM NDYGLYVDPT TQEKSYKRFA PRDNEGIGSV 130 140 150 160 170 180 DFKNFQFNPE ESNSLKYACE RVVEEHEDEV LSVITKENDN LADKLCTEET GLCKEYLHNE L

References

[1]	NIH - Xenopus Gene Collection (XGC) project Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC088697 mRNA. Translation: AAH88697.1.
RefSeq	NP_001088889.1. NM_001095420.1.
UniGene	Xl.87539.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	496234.
KEGG	xla:496234.
Organism-specific databases
CTD	285888.
Xenbase	XB-GENE-981810. cnpy1.
Phylogenomic databases
HOVERGEN	HBG052514.
Family and domain databases
InterPro	IPR021852. DUF3456. [Graphical view]
Pfam	PF11938. DUF3456. 1 hit. [Graphical view]
PROSITE	PS00014. ER_TARGET. 1 hit. PS50015. SAP_B. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CNPY1_XENLA

Accession

Primary (citable) accession number: Q5M7D4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 1, 2005
Last modified:	May 29, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program