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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSTHE264199:G1G41-61-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:stu0047
OrganismiStreptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
Taxonomic identifieri264199 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000001170 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002421011 – 563Arginine--tRNA ligaseAdd BLAST563

Proteomic databases

PRIDEiQ5M6I4

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi264199.stu0047

Structurei

3D structure databases

ProteinModelPortaliQ5M6I4
SMRiQ5M6I4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi121 – 131"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247211
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit

Sequencei

Sequence statusi: Complete.

Q5M6I4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTKELIAAE IAKVVPELEQ ENIQNLLEIP KNADMGDLAF PAFSLAKVLR
60 70 80 90 100
KAPQMIAADI AEKIDASNFE KVEAVGPYIN IFLDKSKISA DVLGQVIAQG
110 120 130 140 150
SHYADQNIGN GRNIAFDMSS PNIAKPFSIG HLRSTVIADA LANIVAKQGY
160 170 180 190 200
KPVRINHLGD WGKQFGMLIV AYKKWGSEEA VKANPINELL QLYVRINAEA
210 220 230 240 250
EEDPSVDEEA REWFRKLEAG DEEATALWQW FRDESLVEFN RLYDELGVSF
260 270 280 290 300
DSYNGEAFYN DKMDEVVDIL TKKGLLQESQ GAQVVNLEKY GIEHPALIKK
310 320 330 340 350
SDGATLYITR DLAAALYRKR TYDFAKAIYV VGNEQSAHFK QLKAVLKEMG
360 370 380 390 400
YNWSDDMTHV AFGLVTKNGK KLSTRKGNVI LLEPTIAEAV NRAQAQIEAK
410 420 430 440 450
NPNLPNKEAI AHAVGVGAIK FYDLKTDRMN GYDFDLDAMV SFEGETGPYV
460 470 480 490 500
QYAHARIQSI LRKADFTPSA DATYSLNDVE SWEIIKLLQD FPRIINRASD
510 520 530 540 550
NFEPSIVAKF AISLAQAFNK YYAHTRILDE SPERDSRLAL CYATATVLKE
560
ALRLLGVEAP DEM
Length:563
Mass (Da):62,892
Last modified:February 1, 2005 - v1
Checksum:i3E7C200F1058C816
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000023 Genomic DNA Translation: AAV59777.1
RefSeqiWP_011225275.1, NC_006448.1

Genome annotation databases

EnsemblBacteriaiAAV59777; AAV59777; stu0047
KEGGistl:stu0047
PATRICifig|264199.4.peg.49

Similar proteinsi

Entry informationi

Entry nameiSYR_STRT2
AccessioniPrimary (citable) accession number: Q5M6I4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: February 1, 2005
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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