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Protein
Submitted name:

Di-or tripeptide:H+ symporter

Gene

dtpT

Organism
Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

TransportUniRule annotation

Protein family/group databases

TCDBi2.A.17.1.6. the proton-dependent oligopeptide transporter (pot/ptr) family.

Names & Taxonomyi

Protein namesi
Submitted name:
Di-or tripeptide:H+ symporterImported
Gene namesi
Name:dtpTImported
Ordered Locus Names:stu0970Imported
OrganismiStreptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)Imported
Taxonomic identifieri264199 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000001170 Componenti: Chromosome

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei27 – 44HelicalSequence analysisAdd BLAST18
Transmembranei56 – 77HelicalSequence analysisAdd BLAST22
Transmembranei97 – 125HelicalSequence analysisAdd BLAST29
Transmembranei146 – 169HelicalSequence analysisAdd BLAST24
Transmembranei175 – 196HelicalSequence analysisAdd BLAST22
Transmembranei220 – 242HelicalSequence analysisAdd BLAST23
Transmembranei248 – 267HelicalSequence analysisAdd BLAST20
Transmembranei279 – 298HelicalSequence analysisAdd BLAST20
Transmembranei327 – 346HelicalSequence analysisAdd BLAST20
Transmembranei358 – 378HelicalSequence analysisAdd BLAST21
Transmembranei390 – 412HelicalSequence analysisAdd BLAST23
Transmembranei424 – 445HelicalSequence analysisAdd BLAST22
Transmembranei451 – 471HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi264199.stu0970.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4APSX-ray3.30A/B1-483[»]
4D2BX-ray2.35A1-483[»]
4D2CX-ray2.47A1-483[»]
4D2DX-ray2.52A1-483[»]
4XNIX-ray2.80A1-483[»]
4XNJX-ray2.30A1-483[»]
5D58X-ray2.40A1-483[»]
5D59X-ray2.40A1-483[»]
5D6KX-ray2.40A1-483[»]
ProteinModelPortaliQ5M4H8.
SMRiQ5M4H8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 201MFSInterPro annotationAdd BLAST201

Sequence similaritiesi

Belongs to the PTR2/POT transporter (TC 2.A.17) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105DUX. Bacteria.
COG3104. LUCA.
HOGENOMiHOG000243451.
KOiK03305.
OMAiYLFAFAK.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR005279. Dipep/tripep_permease.
IPR020846. MFS_dom.
IPR000109. POT_fam.
IPR018456. PTR2_symporter_CS.
[Graphical view]
PANTHERiPTHR11654. PTHR11654. 2 hits.
PfamiPF00854. PTR2. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00924. yjdL_sub1_fam. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS01022. PTR2_1. 1 hit.
PS01023. PTR2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5M4H8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDKGKTFFG QPLGLSTLFM TEMWERFSYY GMRAILLYYM WFLISTGDLH
60 70 80 90 100
ITRATAASIM AIYASMVYLS GTIGGFVADR IIGARPAVFW GGVLIMLGHI
110 120 130 140 150
VLALPFGASA LFGSIILIII GTGFLKPNVS TLVGTLYDEH DRRRDAGFSI
160 170 180 190 200
FVFGINLGAF IAPLIVGAAQ EAAGYHVAFS LAAIGMFIGL LVYYFGGKKT
210 220 230 240 250
LDPHYLRPTD PLAPEEVKPL LVKVSLAVAG FIAIIVVMNL VGWNSLPAYI
260 270 280 290 300
NLLTIVAIAI PVFYFAWMIS SVKVTSTEHL RVVSYIPLFI AAVLFWAIEE
310 320 330 340 350
QGSVVLATFA AERVDSSWFP VSWFQSLNPL FIMLYTPFFA WLWTAWKKNQ
360 370 380 390 400
PSSPTKFAVG LMFAGLSFLL MAIPGALYGT SGKVSPLWLV GSWALVILGE
410 420 430 440 450
MLISPVGLSV TTKLAPKAFN SQMMSMWFLS SSVGSALNAQ LVTLYNAKSE
460 470 480
VAYFSYFGLG SVVLGIVLVF LSKRIQGLMQ GVE
Length:483
Mass (Da):52,749
Last modified:February 1, 2005 - v1
Checksum:i3EB1D527DC05A04B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000023 Genomic DNA. Translation: AAV60632.1.
RefSeqiWP_011225943.1. NC_006448.1.

Genome annotation databases

EnsemblBacteriaiAAV60632; AAV60632; stu0970.
GeneIDi3164310.
KEGGistl:stu0970.
PATRICi19803521. VBIStrThe97850_0963.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000023 Genomic DNA. Translation: AAV60632.1.
RefSeqiWP_011225943.1. NC_006448.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4APSX-ray3.30A/B1-483[»]
4D2BX-ray2.35A1-483[»]
4D2CX-ray2.47A1-483[»]
4D2DX-ray2.52A1-483[»]
4XNIX-ray2.80A1-483[»]
4XNJX-ray2.30A1-483[»]
5D58X-ray2.40A1-483[»]
5D59X-ray2.40A1-483[»]
5D6KX-ray2.40A1-483[»]
ProteinModelPortaliQ5M4H8.
SMRiQ5M4H8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi264199.stu0970.

Protein family/group databases

TCDBi2.A.17.1.6. the proton-dependent oligopeptide transporter (pot/ptr) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV60632; AAV60632; stu0970.
GeneIDi3164310.
KEGGistl:stu0970.
PATRICi19803521. VBIStrThe97850_0963.

Phylogenomic databases

eggNOGiENOG4105DUX. Bacteria.
COG3104. LUCA.
HOGENOMiHOG000243451.
KOiK03305.
OMAiYLFAFAK.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR005279. Dipep/tripep_permease.
IPR020846. MFS_dom.
IPR000109. POT_fam.
IPR018456. PTR2_symporter_CS.
[Graphical view]
PANTHERiPTHR11654. PTHR11654. 2 hits.
PfamiPF00854. PTR2. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00924. yjdL_sub1_fam. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS01022. PTR2_1. 1 hit.
PS01023. PTR2_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5M4H8_STRT2
AccessioniPrimary (citable) accession number: Q5M4H8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 2005
Last sequence update: February 1, 2005
Last modified: November 30, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.