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Q5M348

- TRPC_STRT2

UniProt

Q5M348 - TRPC_STRT2

Protein

Indole-3-glycerol phosphate synthase

Gene

trpC

Organism
Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Feb 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. indole-3-glycerol-phosphate synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciSTHE264199:GI6K-1536-MONOMER.
    UniPathwayiUPA00035; UER00043.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Indole-3-glycerol phosphate synthaseUniRule annotation (EC:4.1.1.48UniRule annotation)
    Short name:
    IGPSUniRule annotation
    Gene namesi
    Name:trpCUniRule annotation
    Ordered Locus Names:stu1590
    OrganismiStreptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
    Taxonomic identifieri264199 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000001170: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 255255Indole-3-glycerol phosphate synthasePRO_1000095901Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi264199.stu1590.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5M348.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpC family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0134.
    HOGENOMiHOG000230462.
    KOiK01609.
    OMAiENGAAMI.
    OrthoDBiEOG6WT8JX.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00134_B. IGPS_B.
    InterProiIPR013785. Aldolase_TIM.
    IPR013798. Indole-3-glycerol_P_synth.
    IPR001468. Indole-3-GlycerolPSynthase_CS.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00218. IGPS. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.
    PROSITEiPS00614. IGPS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5M348-1 [UniParc]FASTAAdd to Basket

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    MSKAFLPTIL EQKGKEVSQL VMEDLQPLRQ TYRLYDFLKS NQNKLQIISE    50
    VKKASPSMGD INLDVDIVAQ AKTYEENGAA MISVLTDEVF FKGDISYLKE 100
    ISTQVAIPTL AKDFIIDEKQ IVRSRNAGAT VILLIVAALP EARLKELYDF 150
    ATSLGLEVLV ETHNLPELEV AHRIGAEIIG VNNRNLVTFE TDINTSLELS 200
    THFKDKPVYI SESAIFTGQD AALVAPYFNG ILVGTALMTA DNVAKKVKEL 250
    QIDKG 255
    Length:255
    Mass (Da):28,188
    Last modified:February 1, 2005 - v1
    Checksum:iFEBDB1A34FA0FA56
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000023 Genomic DNA. Translation: AAV61193.1.
    RefSeqiYP_140008.1. NC_006448.1.

    Genome annotation databases

    EnsemblBacteriaiAAV61193; AAV61193; stu1590.
    GeneIDi3164172.
    KEGGistl:stu1590.
    PATRICi19804729. VBIStrThe97850_1562.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000023 Genomic DNA. Translation: AAV61193.1 .
    RefSeqi YP_140008.1. NC_006448.1.

    3D structure databases

    ProteinModelPortali Q5M348.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 264199.stu1590.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAV61193 ; AAV61193 ; stu1590 .
    GeneIDi 3164172.
    KEGGi stl:stu1590.
    PATRICi 19804729. VBIStrThe97850_1562.

    Phylogenomic databases

    eggNOGi COG0134.
    HOGENOMi HOG000230462.
    KOi K01609.
    OMAi ENGAAMI.
    OrthoDBi EOG6WT8JX.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00043 .
    BioCyci STHE264199:GI6K-1536-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00134_B. IGPS_B.
    InterProi IPR013785. Aldolase_TIM.
    IPR013798. Indole-3-glycerol_P_synth.
    IPR001468. Indole-3-GlycerolPSynthase_CS.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00218. IGPS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    PROSITEi PS00614. IGPS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-250 / LMG 18311.

    Entry informationi

    Entry nameiTRPC_STRT2
    AccessioniPrimary (citable) accession number: Q5M348
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: February 1, 2005
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3