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Q5M1N9

- G6PI_STRT1

UniProt

Q5M1N9 - G6PI_STRT1

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Streptococcus thermophilus (strain CNRZ 1066)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 2 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei291 – 2911Proton donorUniRule annotation
    Active sitei312 – 3121UniRule annotation
    Active sitei426 – 4261UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciSTHE299768:GHWB-245-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:str0194
    OrganismiStreptococcus thermophilus (strain CNRZ 1066)
    Taxonomic identifieri299768 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000001008: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 449449Glucose-6-phosphate isomerasePRO_0000180746Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi299768.str0194.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5M1N9.
    SMRiQ5M1N9. Positions 4-449.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100403.
    KOiK01810.
    OMAiGVESYKR.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5M1N9-1 [UniParc]FASTAAdd to Basket

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    MAHIKFDYSK VLDKFVAPHE VDNLQAQVTV ADEMIRKGTG PGADFLGWRD    50
    LPENYDREEF DRILKAAEKI KEESDVLVVI GIGGSYLGAK AAIDFLSNHF 100
    ANLQTKEERK APQIVYAGNS ISSTYLADLL EYVEGKDFSV NVISKSGTTT 150
    EPAIAFRLFK ELLVKKYGQE EANKRIYATT DRQKGAVKVE ADANGWETFV 200
    VPDDIGGRFS VLTAVGLLPI AVSGADIKAL MEGANAARKE YSSSKISENE 250
    AYQYAAIRNI LYRKGYTTEI LANYEPSLQY FAEWWKQLAG ESEGKDQRGI 300
    YPTSANFSTD LHSLGQFIQE GTRNLFETVV RVDKPRKNVV IPELAEDLDG 350
    LGYLQGKDVD FVNKKATDGV LLAHTDGDVP NMFITIPEQD AFTLGYIIYF 400
    FELAIALSGY LNAVNPFNQP GVEAYKKNMF ALLGKPGFEE LGAELNARL 449
    Length:449
    Mass (Da):49,789
    Last modified:November 8, 2005 - v2
    Checksum:i996EE8CA53C08A8A
    GO

    Sequence cautioni

    The sequence AAV61808.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000024 Genomic DNA. Translation: AAV61808.1. Different initiation.
    RefSeqiYP_140623.1. NC_006449.1.

    Genome annotation databases

    EnsemblBacteriaiAAV61808; AAV61808; str0194.
    GeneIDi3167056.
    KEGGistc:str0194.
    PATRICi19793457. VBIStrThe135799_0205.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000024 Genomic DNA. Translation: AAV61808.1 . Different initiation.
    RefSeqi YP_140623.1. NC_006449.1.

    3D structure databases

    ProteinModelPortali Q5M1N9.
    SMRi Q5M1N9. Positions 4-449.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 299768.str0194.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAV61808 ; AAV61808 ; str0194 .
    GeneIDi 3167056.
    KEGGi stc:str0194.
    PATRICi 19793457. VBIStrThe135799_0205.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100403.
    KOi K01810.
    OMAi GVESYKR.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci STHE299768:GHWB-245-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CNRZ 1066.

    Entry informationi

    Entry nameiG6PI_STRT1
    AccessioniPrimary (citable) accession number: Q5M1N9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2005
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 60 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3