Q5LWM7 (Q5LWM7_SILPO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Betaine aldehyde dehydrogenase EMBL AAV93415.1
EC=1.2.1.8 EMBL AAV93415.1

Gene names

Name:	betB EMBL AAV93415.1
Ordered Locus Names:	SPO0084

Organism

Silicibacter pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) [Complete proteome] [HAMAP]

Taxonomic identifier

246200 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Ruegeria

Protein attributes

Sequence length	484 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Betaine aldehyde + NAD+ + H2O = betaine + NADH. SAAS SAAS011264
Pathway	Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. SAAS SAAS011264
Sequence similarities	Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Ligand	NAD SAAS SAAS011264
Molecular function	Oxidoreductase RuleBase RU003344 SAAS SAAS011264 EMBL AAV93415.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	betaine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	betaine-aldehyde dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5LWM7 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: 22C4E29820DC8859	FASTA	484	51,366
	10 20 30 40 50 60 MKFQPEASHF INGAYVEDTA GAVIDVIYPA TGEVIARLHS ATPAIIDQAL EAARQAQAQW 70 80 90 100 110 120 AAMTGTERGR ILRRAADIMR ARNHDLSVIE THDTGKPIQE TTVADATSGA DALEYFGGLA 130 140 150 160 170 180 GSLTGEHIPL GGGDFAYTVR EALGVCVGIG AWNYPTQIAC WKGAPALACG NTMVFKPSET 190 200 210 220 230 240 TPLSALKVAE ILIEAGAPKG IYNVVQGYGD VGASLVTDPR VAKVSLTGSV PTGRRVYAAA 250 260 270 280 290 300 AESIKHVTME LGGKSPLVVF DDADIENAVS GAILGNFYSS GQVCSNGTRV FVQKGIKEAF 310 320 330 340 350 360 LSRLAERLAT AVIGDPMDPA TNFGPMVSEA QMNIVLGYVD KGKAEGARLV YGGTRLDRDG 370 380 390 400 410 420 FYLLPTVFAD VTDDMTIARE EIFGPVMSVL DFDTEEEVLE RANATEFGLA AGVFTRDITR 430 440 450 460 470 480 AHRMVAGFEA GTCYINSYNL APVEAPFGGS KQSGVGRENS KLAINHFSEM KTVFVSMNDI QAPY

References

[1]

"Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine environment." Moran M.A., Buchan A., Gonzalez J.M., Heidelberg J.F., Whitman W.B., Kiene R.P., Henriksen J.R., King G.M., Belas R., Fuqua C., Brinkac L.M., Lewis M., Johri S., Weaver B., Pai G., Eisen J.A., Rahe E., Sheldon W.M. , Ye W., Miller T.R., Carlton J., Rasko D.A., Paulsen I.T., Ren Q., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Rosovitz M.J., Haft D.H., Selengut J., Ward N. Nature 432:910-913(2004) [PubMed: 15602564] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700808 / DSM 15171 / DSS-3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000031 Genomic DNA. Translation: AAV93415.1.
RefSeq	YP_165358.1. NC_003911.11.
3D structure databases
ProteinModelPortal	Q5LWM7.
SMR	Q5LWM7. Positions 7-484.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3194160.
GenomeReviews	Gene locus SPO0084 in contig CP000031_GR.
KEGG	sil:SPO0084.
NMPDR	fig|246200.3.peg.477.
PATRIC	23373405. VBIRuePom114501_0088.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG752218.
OMA	IMRERNR.
ProtClustDB	PRK13252.
Enzyme and pathway databases
BioCyc	RPOM246200:SPO_0084-MONOMER.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR011264. Betaine_Ald_DH. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00130.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMs	TIGR01804. BADH. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5LWM7_SILPO

Accession

Primary (citable) accession number: Q5LWM7

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)