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Q5LVN3

- SYH_RUEPO

UniProt

Q5LVN3 - SYH_RUEPO

Protein

Histidine--tRNA ligase

Gene

hisS

Organism
Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (01 Feb 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. histidine-tRNA ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. histidyl-tRNA aminoacylation Source: InterPro

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histidine--tRNA ligaseUniRule annotation (EC:6.1.1.21UniRule annotation)
    Alternative name(s):
    Histidyl-tRNA synthetaseUniRule annotation
    Short name:
    HisRSUniRule annotation
    Gene namesi
    Name:hisSUniRule annotation
    Ordered Locus Names:SPO0667
    OrganismiRuegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
    Taxonomic identifieri246200 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRuegeria
    ProteomesiUP000001023: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 495495Histidine--tRNA ligasePRO_0000136248Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi246200.SPO0667.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5LVN3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class-II aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0124.
    HOGENOMiHOG000018071.
    KOiK01892.
    OMAiIIRYVSF.
    OrthoDBiEOG6BPDH4.

    Family and domain databases

    Gene3Di3.40.50.800. 1 hit.
    HAMAPiMF_00127. His_tRNA_synth.
    InterProiIPR006195. aa-tRNA-synth_II.
    IPR004154. Anticodon-bd.
    IPR015807. His-tRNA-ligase.
    IPR004516. HisRS/HisZ.
    [Graphical view]
    PANTHERiPTHR11476. PTHR11476. 1 hit.
    PfamiPF03129. HGTP_anticodon. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001549. His-tRNA_synth. 1 hit.
    SUPFAMiSSF52954. SSF52954. 1 hit.
    TIGRFAMsiTIGR00442. hisS. 1 hit.
    PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5LVN3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKPKKTPRP KAETPKGFRD YFGAEVTQRT EMLRDIAGVY HRYGFEALES    50
    SAVETVEALG KFLPDVDRPN EGVFAWQESE DDGAGDWMAL RYDLTAPLAR 100
    VYAQHRNDLP TPYRRYAMGP VWRNEKPGPG RYRQFYQCDA DTVGSASMAA 150
    DAEICAMLSD TLETVGIPRG DYVVRVNNRK VLNGVLETMG LADEGQRDAV 200
    LRTIDKFDKV GEDGVRELLG KGRLDASGAF IDGVGLSDDQ AGPVLAFLTS 250
    RGADAATTVA NLRAAVGASQ IGVQGIDELE QIGDLLAAGG YGPDRIVIDP 300
    SVVRGLGYYT GPVYEAELTF EIFDEKGRKR QFGSVSGGGR YDDLVKRFTG 350
    QEVPATGVSI GVDRLLAALR EKGRIRTAER GPVVVTVMDR DRMADYQAMV 400
    AELRNAGIRA EVYLGNPKNF GNQLKYADKR NSPVAVIEGG DERANGVVQI 450
    KDLILGAQIA ANATLEEWKE RPSQYEVARA DLVAKVREIL AEQAG 495
    Length:495
    Mass (Da):53,962
    Last modified:February 1, 2005 - v1
    Checksum:i0BD396AF615967FE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000031 Genomic DNA. Translation: AAV93975.1.
    RefSeqiYP_165922.1. NC_003911.12.

    Genome annotation databases

    EnsemblBacteriaiAAV93975; AAV93975; SPO0667.
    GeneIDi3192980.
    KEGGisil:SPO0667.
    PATRICi23374601. VBIRuePom114501_0674.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000031 Genomic DNA. Translation: AAV93975.1 .
    RefSeqi YP_165922.1. NC_003911.12.

    3D structure databases

    ProteinModelPortali Q5LVN3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 246200.SPO0667.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAV93975 ; AAV93975 ; SPO0667 .
    GeneIDi 3192980.
    KEGGi sil:SPO0667.
    PATRICi 23374601. VBIRuePom114501_0674.

    Phylogenomic databases

    eggNOGi COG0124.
    HOGENOMi HOG000018071.
    KOi K01892.
    OMAi IIRYVSF.
    OrthoDBi EOG6BPDH4.

    Family and domain databases

    Gene3Di 3.40.50.800. 1 hit.
    HAMAPi MF_00127. His_tRNA_synth.
    InterProi IPR006195. aa-tRNA-synth_II.
    IPR004154. Anticodon-bd.
    IPR015807. His-tRNA-ligase.
    IPR004516. HisRS/HisZ.
    [Graphical view ]
    PANTHERi PTHR11476. PTHR11476. 1 hit.
    Pfami PF03129. HGTP_anticodon. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001549. His-tRNA_synth. 1 hit.
    SUPFAMi SSF52954. SSF52954. 1 hit.
    TIGRFAMsi TIGR00442. hisS. 1 hit.
    PROSITEi PS50862. AA_TRNA_LIGASE_II. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700808 / DSM 15171 / DSS-3.

    Entry informationi

    Entry nameiSYH_RUEPO
    AccessioniPrimary (citable) accession number: Q5LVN3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 6, 2005
    Last sequence update: February 1, 2005
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3