Q5LVC2 (PHNC_RUEPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphonates import ATP-binding protein PhnC
EC=3.6.3.28

Gene names

Name:	phnC
Synonyms:	phoC
Ordered Locus Names:	SPO0780

Organism

Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) [Complete proteome] [HAMAP]

Taxonomic identifier

246200 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Ruegeria › Ruegeria pomeroyi

Protein attributes

Sequence length	273 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system By similarity.
Catalytic activity	ATP + H2O + phosphonate(Out) = ADP + phosphate + phosphonate(In).
Subunit structure	The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD) Potential.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. [View classification] Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Phosphonate transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW organic phosphonate transmembrane-transporting ATPase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 273	273	Phosphonates import ATP-binding protein PhnC		PRO_0000274754
Regions
	Domain	2 – 245	244	ABC transporter
	Nucleotide binding	34 – 41	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5LVC2 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: AA1CF7E2F4F698B9	FASTA	273	29,962
	10 20 30 40 50 60 MLRIDKLTKR FGDNIAVNAA TLDVDKPCMI GIIGRSGAGK STLLRMINRL SDATDGRILF 70 80 90 100 110 120 EDRDVTRLRG AEKRAWQAQC AMIFQQFNLV PRMDVVSNVL HGTLNRRSTL ATMFNLYPTE 130 140 150 160 170 180 DIHRAIDILD RLGIAAHAAK RAEALSGGQQ QRVAIARALM QDPAIILADE PIASLDPMNA 190 200 210 220 230 240 QVVMQALRRI HEEDGRTVIA NLHTLDTARR YCDRVVGMRD GRIVFDGLPE QLTTGVAREI 250 260 270 YGADASFSEA ATSTEIDTLD AALPARQRAG ATA

References

[1]

"Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine environment." Moran M.A., Buchan A., Gonzalez J.M., Heidelberg J.F., Whitman W.B., Kiene R.P., Henriksen J.R., King G.M., Belas R., Fuqua C., Brinkac L.M., Lewis M., Johri S., Weaver B., Pai G., Eisen J.A., Rahe E., Sheldon W.M. , Ye W., Miller T.R., Carlton J., Rasko D.A., Paulsen I.T., Ren Q., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Rosovitz M.J., Haft D.H., Selengut J., Ward N. Nature 432:910-913(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700808 / DSM 15171 / DSS-3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000031 Genomic DNA. Translation: AAV94085.1.
RefSeq	YP_166033.1. NC_003911.11.
3D structure databases
HSSP	HSSP built from PDB template 1G6H based on UniProtKB Q58663.
ProteinModelPortal	Q5LVC2.
ModBase	Search...
Protein-protein interaction databases
STRING	246200.SPO0780.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAV94085; AAV94085; SPO0780.
GeneID	3195497.
KEGG	sil:SPO0780.
PATRIC	23374835. VBIRuePom114501_0789.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3638.
KO	K02041.
OMA	FNLVPRM.
ProtClustDB	CLSK933352.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR012693. ABC_transpr_PhnC. [Graphical view]
Pfam	PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
TIGRFAMs	TIGR02315. ABC_phnC. 1 hit.
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. PS51249. PHNC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHNC_RUEPO

Accession

Primary (citable) accession number: Q5LVC2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
Last sequence update:	February 1, 2005
Last modified:	May 1, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program