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Q5LRS9 (G6PI_RUEPO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:SPO2046
OrganismRuegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) [Complete proteome] [HAMAP]
Taxonomic identifier246200 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRuegeria

Protein attributes

Sequence length539 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 539539Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180725

Sites

Active site3401Proton donor By similarity
Active site3711 By similarity
Active site5001 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5LRS9 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 8E8D7CFAFF6DB47F

FASTA53958,354
        10         20         30         40         50         60 
MFQDLHALHT RTSGRRILDL FAADLRRAER FSADLGEMRL DYSKTQIDDA IRAGLIALCD 

        70         80         90        100        110        120 
RAQLADKREA MFAGAPINET EGRAVLHTAL RNLDGGPVHV DGAEVMADVR LTLARMRRFA 

       130        140        150        160        170        180 
EALRSGALPG AGGAITDVVN IGIGGSDLGP AMAVLALAPY HDGPRCHFVS NVDGAHIADT 

       190        200        210        220        230        240 
LRGLDPARTL VIVASKTFTT IETMTNARTA RDWMQRGGGD PERQFAAVST ATDRTAAFGI 

       250        260        270        280        290        300 
PGDRVFGFAD WVGGRYSLWG PIGLSLMIAI GPDDFDAFLR GAQEMDRHFQ SAPWEKNLPV 

       310        320        330        340        350        360 
MLALTGIWHH QICGHPSRAV LPYDQRLARL PAYLQQLEME SNGKSVAMDG TALDQAAGPI 

       370        380        390        400        410        420 
VWGEPGTNGQ HAFYQLIHQG KQVVPCEFMV AARGHEPDLA HHHRLLIANC LAQSEALMRG 

       430        440        450        460        470        480 
RPLDEARAIA AARGVAGDEL ERQARHRVFA GNRPSTTLIY PRLTPAMLGR IIALYEHRVF 

       490        500        510        520        530 
VEGVILGINS FDQWGVELGK ELATSLGPVV DGTESAAAKD GSTAALVDYV LAHRDTDLT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000031 Genomic DNA. Translation: AAV95317.1.
RefSeqYP_167276.1. NC_003911.12.

3D structure databases

ProteinModelPortalQ5LRS9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING246200.SPO2046.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAV95317; AAV95317; SPO2046.
GeneID3195577.
KEGGsil:SPO2046.
PATRIC23377431. VBIRuePom114501_2072.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OrthoDBEOG64R61J.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_RUEPO
AccessionPrimary (citable) accession number: Q5LRS9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: February 1, 2005
Last modified: June 11, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways