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Q5LQI6 (SYR_RUEPO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:SPO2504
OrganismRuegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) [Complete proteome] [HAMAP]
Taxonomic identifier246200 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRuegeria

Protein attributes

Sequence length581 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 581581Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242093

Regions

Motif131 – 14111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q5LQI6 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 50C3507B458CBA82

FASTA58163,585
        10         20         30         40         50         60 
MNLFTEMRGL VLEALEQMQA EGALPQGLDF ANVAVEPPRD AAHGDMATNA AMVLAKPAGQ 

        70         80         90        100        110        120 
KPRDIAETLA ARLAADARVA KAEVAGPGFL NLTLAAPVWQ RVVGTVLLDG TAYGRSDMGQ 

       130        140        150        160        170        180 
GKKVNVEYVS ANPTGPLHVG HTRGAVFGDA LASLLDYAGY QVTREYYIND GGAQVDVLAR 

       190        200        210        220        230        240 
SVYLRYLEAH GQAVEFVDGT YPGEYLVEVG QALKDKVGDA YVGQPEEVWL EAIRDFATDA 

       250        260        270        280        290        300 
MMELIRADLA QLGVKMDVFY SEKSLYGTGR IEAAIDSLRA KGLIYRGTLE PPKGKLPEDW 

       310        320        330        340        350        360 
EPREQTLFKS TEHGDDVDRP IMKSDGAWTY FAPDIAYHYD KVSRGFDALI DVFGADHGGY 

       370        380        390        400        410        420 
VKRMKAAVSA LSDGRVPLDI KLCQLVKLWK NGEPFKMSKR AGNFVTLRDV VDQVGADVTR 

       430        440        450        460        470        480 
FVMLTRKNDA PLDFDFDKVL EQSRENPVFY VQYAHARVSS VLRRAAEAGI DTSDTALRAA 

       490        500        510        520        530        540 
DLGLLGHEAE LAVMRKLAEW PRLVEIAART NEPHRIAFYL YELAGDFHAL WNRGNDVSEL 

       550        560        570        580 
RFIQDGDEGT SQAKIALARS VAVVISAGLA ILGVTPAEEM R 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000031 Genomic DNA. Translation: AAV95754.1.
RefSeqYP_167719.1. NC_003911.12.

3D structure databases

ProteinModelPortalQ5LQI6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING246200.SPO2504.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAV95754; AAV95754; SPO2504.
GeneID3193911.
KEGGsil:SPO2504.
PATRIC23378407. VBIRuePom114501_2553.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAPRVKGAI.
OrthoDBEOG6JB13C.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_RUEPO
AccessionPrimary (citable) accession number: Q5LQI6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: February 1, 2005
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries