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Reviewed, UniProtKB/Swiss-Prot Q5LPG8 (ASPD_SILPO)

Last modified November 25, 2008. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable L-aspartate dehydrogenase
    EC=1.4.1.21
Gene names
Name: nadX
Ordered Locus Names: SPO2880
OrganismSilicibacter pomeroyi [Complete proteome] [HAMAP]
Taxonomic identifier89184 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeSilicibacter

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity.

Catalytic activity

L-aspartate + H(2)O + NAD(P)(+) = oxaloacetate + NH(3) + NAD(P)H.

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1.

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity.

Sequence similarities

Belongs to the L-aspartate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 275275Probable L-aspartate dehydrogenase
PRO_0000144892

Sites

Active site2261 By similarity
Binding site1301NAD; via amide nitrogen By similarity
Binding site1961NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5LPG8-1 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: D98084319F319CD8

FASTA27527,808
        10         20         30         40         50         60 
MWKLWGSWPE GDRVRIALIG HGPIAAHVAA HLPVGVQLTG ALCRPGRDDA ARAALGVSVA 

        70         80         90        100        110        120 
QALEGLPQRP DLLVDCAGHS GLRAHGLTAL GAGVEVLTVS VGALADAVFC AELEDAARAG 

       130        140        150        160        170        180 
GTRLCLASGA IGALDALAAA AMGTGLQVTY TGRKPPQGWR GSRAEKVLDL KALTGPVTHF 

       190        200        210        220        230        240 
TGTARAAAQA YPKNANVAAA VALAGAGLDA TRAELIADPG AAANIHEIAA EGAFGRFRFQ 

       250        260        270 
IEGLPLPGNP RSSALTALSL LAALRQRGAA IRPSF 

« Hide

Cross-references

Sequence databases

CP000031 Genomic DNA. Translation: AAV96121.1.
RefSeqYP_168088.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3195767.
GenomeReviewsGene locus SPO2880 in contig CP000031_GR.
KEGGsil:SPO2880.
NMPDRfig|246200.3.peg.3822.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ5LPG8.

Enzyme and pathway databases

BioCycSPOM246200:SPO_2880-MON.

Family and domain databases

HAMAPMF_01265.
[Tree]
InterProIPR005106. Asp/hSer_DHase_NAD-bd.
IPR002811. Asp_DHase.
IPR011182. Asp_DHase_NAD_syn.
[Graphical view]
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProDomPD017325. Asp_dh. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameASPD_SILPO
AccessionPrimary (citable) accession number: Q5LPG8
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: February 1, 2005
Last modified: November 25, 2008
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents