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Q5LM24 (Q5LM24_SILPO) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA 2 HAMAP MF_01401

Short name=Protein-methionine-S-oxide reductase 2 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 2 HAMAP MF_01401
Gene names
Name:msrA-2 EMBL AAV96961.1
Synonyms:msrA2 HAMAP MF_01401
Ordered Locus Names:SPO3740
OrganismSilicibacter pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) [Complete proteome] [HAMAP]
Taxonomic identifier246200 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRuegeria

Protein attributes

Sequence length170 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site121 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
Q5LM24 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 6F159353CFC4354F

FASTA17019,208
        10         20         30         40         50         60 
MSLERAVLAG GCFWGMQDLI RKMPGVDRTR VGYTGGDVPN ATYRNHGSHA EGIEIWFDPT 

        70         80         90        100        110        120 
RISFRQLLEF FFQIHDPTTV NRQGNDLGTS YRSAIYYVDE AQKAVALDTI ADVDASGLWP 

       130        140        150        160        170 
GRVVTEVEPV GDFWEAEENH QDYLEKHPNG YTCHFARADW VLPKRADAAE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000031 Genomic DNA. Translation: AAV96961.1.
RefSeqYP_168934.1. NC_003911.11.

3D structure databases

ProteinModelPortalQ5LM24.
SMRQ5LM24. Positions 2-165.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3195621.
GenomeReviewsGene locus SPO3740 in contig CP000031_GR.
KEGGsil:SPO3740.
NMPDRfig|246200.3.peg.4188.
PATRIC23380973. VBIRuePom114501_3819.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG748152.
OMAYRQILEF.
ProtClustDBPRK14054.

Enzyme and pathway databases

BioCycRPOM246200:SPO_3740-MONOMER.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ5LM24_SILPO
AccessionPrimary (citable) accession number: Q5LM24
Entry history
Integrated into UniProtKB/TrEMBL: February 1, 2005
Last sequence update: February 1, 2005
Last modified: December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)