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Protein

Adenine deaminase

Gene

ade

Organism
Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandManganese

Enzyme and pathway databases

BioCyciRPOM246200:G1G48-3805-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:SPO3746
OrganismiRuegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Taxonomic identifieri246200 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRuegeria
Proteomesi
  • UP000001023 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001424371 – 603Adenine deaminaseAdd BLAST603

Proteomic databases

PRIDEiQ5LM18

Interactioni

Protein-protein interaction databases

STRINGi246200.SPO3746

Structurei

3D structure databases

SMRiQ5LM18
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN Bacteria
COG1001 LUCA
HOGENOMiHOG000276949
KOiK01486
OMAiSSMVTAC
OrthoDBiPOG091H00I8

Family and domain databases

CDDicd01295 AdeC, 1 hit
Gene3Di2.30.40.10, 2 hits
HAMAPiMF_01518 Adenine_deamin, 1 hit
InterProiView protein in InterPro
IPR006679 Adenine_deam
IPR026912 Adenine_deam_C
IPR006680 Amidohydro-rel
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PfamiView protein in Pfam
PF13382 Adenine_deam_C, 1 hit
PF01979 Amidohydro_1, 1 hit
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit
TIGRFAMsiTIGR01178 ade, 1 hit

Sequencei

Sequence statusi: Complete.

Q5LM18-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPTTFPSWA DVAPRLVAVA AGREPADMII RNGTWINVHT REALPGHSIA
60 70 80 90 100
IAEGRIAFVG PDASHCSGPD TRIIEANGRY MIPGLCDGHM HIESGMLTPA
110 120 130 140 150
EFAAAVIPHG TTTMFTDPHE IANVLGLAGV RMMHDEALMQ PVNIFTQMPS
160 170 180 190 200
CAPSAPGLET TGYEITPEDV AEAMTWPGII GLGEMMNFPG VTNADPKMLA
210 220 230 240 250
EIAATQRAGK TVGGHYASPD LGPAFAAYVA GGPADDHEGT CEADAIARVR
260 270 280 290 300
QGMRSMMRLG SAWYDVETQI TAVTEKGLDP RNFILCTDDC HSATLVNDGH
310 320 330 340 350
MNRVVRHAIA CGCDPLIALQ MATINTATHF GLERELGSTA PGRRADVILT
360 370 380 390 400
SDLRDLPIEL VIARGQVVAE NGKIAVDCPH YDWPDTARGT VHLGHALSAR
410 420 430 440 450
DFEIAAPTGA NRVRANVIGV VENQAPTKAL KAELPVREGL VETAEHPDDV
460 470 480 490 500
CQIALVERHR ATGGVTNAFV SGFGYQGRMA MASTVAHDSH HMIVVGTDRE
510 520 530 540 550
QMALAANRLA EVGGGITIWR DGQELALVEL PIAGLMSDSP AAEVAAKAQA
560 570 580 590 600
MVEAMAACGC TLNNAYMQHS LLALVVIPEL RISDLGLIDV RSFERIDLLE

PLA
Length:603
Mass (Da):64,109
Last modified:October 14, 2015 - v2
Checksum:iDE5B2FDFF8106791
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000031 Genomic DNA Translation: AAV96967.2
RefSeqiWP_030003271.1, NC_003911.12

Genome annotation databases

EnsemblBacteriaiAAV96967; AAV96967; SPO3746
KEGGisil:SPO3746

Similar proteinsi

Entry informationi

Entry nameiADEC_RUEPO
AccessioniPrimary (citable) accession number: Q5LM18
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 12, 2005
Last sequence update: October 14, 2015
Last modified: May 23, 2018
This is version 80 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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