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Protein

Adenine deaminase

Gene

ade

Organism
Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:SPO3746
OrganismiRuegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Taxonomic identifieri246200 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRuegeria
Proteomesi
  • UP000001023 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001424371 – 603Adenine deaminaseAdd BLAST603

Interactioni

Protein-protein interaction databases

STRINGi246200.SPO3746.

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiPFIRVTP.
OrthoDBiPOG091H00I8.

Family and domain databases

CDDicd01295. AdeC. 1 hit.
Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5LM18-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPTTFPSWA DVAPRLVAVA AGREPADMII RNGTWINVHT REALPGHSIA
60 70 80 90 100
IAEGRIAFVG PDASHCSGPD TRIIEANGRY MIPGLCDGHM HIESGMLTPA
110 120 130 140 150
EFAAAVIPHG TTTMFTDPHE IANVLGLAGV RMMHDEALMQ PVNIFTQMPS
160 170 180 190 200
CAPSAPGLET TGYEITPEDV AEAMTWPGII GLGEMMNFPG VTNADPKMLA
210 220 230 240 250
EIAATQRAGK TVGGHYASPD LGPAFAAYVA GGPADDHEGT CEADAIARVR
260 270 280 290 300
QGMRSMMRLG SAWYDVETQI TAVTEKGLDP RNFILCTDDC HSATLVNDGH
310 320 330 340 350
MNRVVRHAIA CGCDPLIALQ MATINTATHF GLERELGSTA PGRRADVILT
360 370 380 390 400
SDLRDLPIEL VIARGQVVAE NGKIAVDCPH YDWPDTARGT VHLGHALSAR
410 420 430 440 450
DFEIAAPTGA NRVRANVIGV VENQAPTKAL KAELPVREGL VETAEHPDDV
460 470 480 490 500
CQIALVERHR ATGGVTNAFV SGFGYQGRMA MASTVAHDSH HMIVVGTDRE
510 520 530 540 550
QMALAANRLA EVGGGITIWR DGQELALVEL PIAGLMSDSP AAEVAAKAQA
560 570 580 590 600
MVEAMAACGC TLNNAYMQHS LLALVVIPEL RISDLGLIDV RSFERIDLLE

PLA
Length:603
Mass (Da):64,109
Last modified:October 14, 2015 - v2
Checksum:iDE5B2FDFF8106791
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000031 Genomic DNA. Translation: AAV96967.2.
RefSeqiWP_030003271.1. NC_003911.12.

Genome annotation databases

EnsemblBacteriaiAAV96967; AAV96967; SPO3746.
KEGGisil:SPO3746.
PATRICi23380985. VBIRuePom114501_3825.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000031 Genomic DNA. Translation: AAV96967.2.
RefSeqiWP_030003271.1. NC_003911.12.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi246200.SPO3746.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV96967; AAV96967; SPO3746.
KEGGisil:SPO3746.
PATRICi23380985. VBIRuePom114501_3825.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiPFIRVTP.
OrthoDBiPOG091H00I8.

Family and domain databases

CDDicd01295. AdeC. 1 hit.
Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiADEC_RUEPO
AccessioniPrimary (citable) accession number: Q5LM18
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 12, 2005
Last sequence update: October 14, 2015
Last modified: November 2, 2016
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.