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Q5LLZ3 (UPPP_RUEPO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:SPO3771
OrganismRuegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) [Complete proteome] [HAMAP]
Taxonomic identifier246200 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRuegeria

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 267267Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151197

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane40 – 6021Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane111 – 13121Helical; Potential
Transmembrane190 – 21021Helical; Potential
Transmembrane219 – 23921Helical; Potential
Transmembrane245 – 26521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q5LLZ3 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 87AF1C9083EE2C27

FASTA26728,079
        10         20         30         40         50         60 
MSLFHLILVA LIQGITEFLP VSSSGHLILL PALTGLEDQG QVIDVAVHVG TLGAVVLYFW 

        70         80         90        100        110        120 
RDVRDGLAGL PRALTGRLDT PGARLAMGLI VATIPTVLAG AALHFTGLSD ALRSITVIGW 

       130        140        150        160        170        180 
TMLLFGLLLW WADRTGAQVK EATDWSLRDA LILGLWQAVA LIPGTSRSGI TITGARAMGY 

       190        200        210        220        230        240 
TRSDGARISM LMSIPTIIAS GVLLGADVAV TSDAQAARDG AIAAAFAFVS ALLALSLMMR 

       250        260 
LLRSVSFTPY VIYRLALGLV LLGIAYS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000031 Genomic DNA. Translation: AAV96992.1.
RefSeqYP_168966.1. NC_003911.12.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING246200.SPO3771.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAV96992; AAV96992; SPO3771.
GeneID3196513.
KEGGsil:SPO3771.
PATRIC23381039. VBIRuePom114501_3852.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OrthoDBEOG6QP13M.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_RUEPO
AccessionPrimary (citable) accession number: Q5LLZ3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: February 1, 2005
Last modified: May 14, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families