Q5LLN1 (Q5LLN1_SILPO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Shikimate dehydrogenase HAMAP MF_00222
EC=1.1.1.25 HAMAP MF_00222

Gene names

Name:	aroE HAMAP MF_00222 EMBL AAV97104.1
Ordered Locus Names:	SPO3891

Organism

Silicibacter pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) [Complete proteome] [HAMAP]

Taxonomic identifier

246200 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Ruegeria

Protein attributes

Sequence length	277 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222 SAAS SAAS011342
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222 SAAS SAAS011342
Sequence similarities	Belongs to the shikimate dehydrogenase family. HAMAP MF_00222

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00222 SAAS SAAS011342
Ligand	NADP HAMAP MF_00222 SAAS SAAS011342
Molecular function	Oxidoreductase RuleBase RU004037 HAMAP MF_00222 SAAS SAAS011342 EMBL AAV97104.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	133 – 137	5	NADP By similarity HAMAP MF_00222
Sites
	Active site	70	1	Proton acceptor By similarity HAMAP MF_00222

Sequences

	Sequence		Length	Mass (Da)
	Q5LLN1 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: E14992A5B19E8D76	FASTA	277	29,635
	10 20 30 40 50 60 MTENRIPLAG VIGHPISHSK SPRLHGHWLK TYGINGHYIP MDVAPQDLAQ VVRTLPKAGF 70 80 90 100 110 120 VGVNITIPHK EAVMSVADQI TDRATLIGAV NTLIFREDGR ILADNTDGYG FMENLRAGAP 130 140 150 160 170 180 GWDPKSGPAV VFGAGGAARA VISALAEAGV PEVIVTNRTR VRADKLKDDF GQRVTVADWV 190 200 210 220 230 240 QAGNVIEDAR LVVNTTSLGM IGKPELRVPL DGLRADAVVT DLVYAPLKTR LLAEAEEMGC 250 260 270 TTVDGLGMLL HQAVPGFERW FGERPVVDAA TRAAALR

References

[1]

"Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine environment." Moran M.A., Buchan A., Gonzalez J.M., Heidelberg J.F., Whitman W.B., Kiene R.P., Henriksen J.R., King G.M., Belas R., Fuqua C., Brinkac L.M., Lewis M., Johri S., Weaver B., Pai G., Eisen J.A., Rahe E., Sheldon W.M. , Ye W., Miller T.R., Carlton J., Rasko D.A., Paulsen I.T., Ren Q., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Rosovitz M.J., Haft D.H., Selengut J., Ward N. Nature 432:910-913(2004) [PubMed: 15602564] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700808 / DSM 15171 / DSS-3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000031 Genomic DNA. Translation: AAV97104.1.
RefSeq	YP_169079.1. NC_003911.11.
3D structure databases
ProteinModelPortal	Q5LLN1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3196139.
GenomeReviews	Gene locus SPO3891 in contig CP000031_GR.
KEGG	sil:SPO3891.
NMPDR	fig|246200.3.peg.3978.
PATRIC	23381289. VBIRuePom114501_3970.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG553408.
OMA	GHYIPMD.
ProtClustDB	PRK00258.
Enzyme and pathway databases
BioCyc	RPOM246200:SPO_3891-MONOMER.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR011342. Shikimate_DH. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. IPR006151. Shikm_DH/Glu-tRNA_Rdtase. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00014.
Pfam	PF01488. Shikimate_DH. 1 hit. PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00507. AroE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q5LLN1_SILPO

Accession

Primary (citable) accession number: Q5LLN1

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	December 14, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)