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Protein
Submitted name:

Gentisate 1,2-dioxygenase

Gene

gtdA-2

Organism
Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi119 – 1191Iron 1; via tele nitrogenCombined sources
Metal bindingi121 – 1211Iron 1; via tele nitrogenCombined sources
Metal bindingi160 – 1601Iron 1; via tele nitrogenCombined sources
Metal bindingi290 – 2901Iron 2; via tele nitrogenCombined sources
Metal bindingi292 – 2921Iron 2; via tele nitrogenCombined sources
Metal bindingi330 – 3301Iron 2; via tele nitrogenCombined sources

GO - Molecular functioni

  • gentisate 1,2-dioxygenase activity Source: TIGR
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

  • cellular aromatic compound metabolic process Source: TIGR
Complete GO annotation...

Keywords - Molecular functioni

DioxygenaseImported, Oxidoreductase

Keywords - Ligandi

IronCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BRENDAi1.13.11.4. 8123.

Names & Taxonomyi

Protein namesi
Submitted name:
Gentisate 1,2-dioxygenaseImported (EC:1.13.11.4Imported)
Gene namesi
Name:gtdA-2Imported
Ordered Locus Names:SPOA0115Imported
Encoded oniPlasmid megaplasmid SpoImported
OrganismiRuegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)Imported
Taxonomic identifieri246200 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRuegeria
Proteomesi
  • UP000001023 Componenti: Plasmid megaplasmid Spo

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi100 ↔ 323Combined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3BU7X-ray2.80A/B1-374[»]
ProteinModelPortaliQ5LLB1.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5LLB1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini107 – 17771Cupin_2InterPro annotationAdd
BLAST
Domaini278 – 34366Cupin_2InterPro annotationAdd
BLAST

Phylogenomic databases

HOGENOMiHOG000173721.
KOiK00450.
OMAiQDGLDIP.
OrthoDBiEOG6Z3KFW.

Family and domain databases

Gene3Di2.60.120.10. 2 hits.
InterProiIPR013096. Cupin_2.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF07883. Cupin_2. 2 hits.
[Graphical view]
SUPFAMiSSF51182. SSF51182. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5LLB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPTEIKPED DILGRARVRD TPELEAYYDD LAKIETGALW TVANDIEPWE
60 70 80 90 100
PTPKSAPVHW KWSDLRREVL RAIDLVRPED AGRRVVYLRN PQRKDVSAAC
110 120 130 140 150
GWLFSGIQTM KAGERAGAHR HAASALRFIM EGSGAYTIVD GHKVELGAND
160 170 180 190 200
FVLTPNGTWH EHGILESGTE CIWQDGLDIP LTNCLEANFY EVHPNDYQTT
210 220 230 240 250
DIPLNDSPLT YGGPALLPQL DKWDKPYSPL LKYSWEPTYE ALLNYAKASD
260 270 280 290 300
GSPYDGLILR YTNPQTGGHP MLTMGASMQM LRPGEHTKAH RHTGNVIYNV
310 320 330 340 350
AKGQGYSIVG GKRFDWSEHD IFCVPAWTWH EHCNTQERDD ACLFSFNDFP
360 370
VMEKLGFWAE QALEDNGGHQ IVAD
Length:374
Mass (Da):42,092
Last modified:February 1, 2005 - v1
Checksum:iFA5FCE2CDA680138
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000032 Genomic DNA. Translation: AAV97252.1.
RefSeqiWP_011241898.1. NC_006569.1.

Genome annotation databases

EnsemblBacteriaiAAV97252; AAV97252; SPOA0115.
KEGGisil:SPOA0115.
PATRICi23381552. VBIRuePom114501_4100.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000032 Genomic DNA. Translation: AAV97252.1.
RefSeqiWP_011241898.1. NC_006569.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3BU7X-ray2.80A/B1-374[»]
ProteinModelPortaliQ5LLB1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAV97252; AAV97252; SPOA0115.
KEGGisil:SPOA0115.
PATRICi23381552. VBIRuePom114501_4100.

Phylogenomic databases

HOGENOMiHOG000173721.
KOiK00450.
OMAiQDGLDIP.
OrthoDBiEOG6Z3KFW.

Enzyme and pathway databases

BRENDAi1.13.11.4. 8123.

Miscellaneous databases

EvolutionaryTraceiQ5LLB1.

Family and domain databases

Gene3Di2.60.120.10. 2 hits.
InterProiIPR013096. Cupin_2.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamiPF07883. Cupin_2. 2 hits.
[Graphical view]
SUPFAMiSSF51182. SSF51182. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700808 / DSM 15171 / DSS-3Imported.
  2. "Crystal structure and mutagenic analysis of GDOsp, a gentisate 1,2-dioxygenase from Silicibacter pomeroyi."
    Chen J., Li W., Wang M., Zhu G., Liu D., Sun F., Hao N., Li X., Rao Z., Zhang X.C.
    Protein Sci. 17:1362-1373(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) IN COMPLEX WITH IRON, DISULFIDE BONDS.
  3. "An updated genome annotation for the model marine bacterium Ruegeria pomeroyi DSS-3."
    Rivers A.R., Smith C.B., Moran M.A.
    Stand. Genomic Sci. 9:11-11(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 700808 / DSM 15171 / DSS-3Imported.

Entry informationi

Entry nameiQ5LLB1_RUEPO
AccessioniPrimary (citable) accession number: Q5LLB1
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 2005
Last sequence update: February 1, 2005
Last modified: March 16, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, PlasmidImported, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.