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Q5LJ30 (UPPP_BACFN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:BF0068
OrganismBacteroides fragilis (strain ATCC 25285 / NCTC 9343) [Complete proteome] [HAMAP]
Taxonomic identifier272559 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides

Protein attributes

Sequence length266 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 266266Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000227605

Regions

Transmembrane41 – 6121Helical; Potential
Transmembrane82 – 10221Helical; Potential
Transmembrane106 – 12621Helical; Potential
Transmembrane140 – 16021Helical; Potential
Transmembrane180 – 20021Helical; Potential
Transmembrane213 – 23321Helical; Potential
Transmembrane245 – 26521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q5LJ30 [UniParc].

Last modified June 21, 2005. Version 1.
Checksum: 06A5F948C9F99616

FASTA26628,752
        10         20         30         40         50         60 
MEWFEALILG LIQGLTEYLP VSSSGHLAIG SALFGIEGEE NLAFTIVVHV ATVFSTLVIL 

        70         80         90        100        110        120 
WKEIDWIFRG LFKFEMNSET RYVINILISM IPIGIVGVFF KDEVEAIFGS GLLIVGCMLL 

       130        140        150        160        170        180 
LTAALLSFSY YAKPRQKENI SMKDAFIIGL AQACAVLPGL SRSGSTIATG LLLGDNKAKL 

       190        200        210        220        230        240 
AQFSFLMVIP PILGEALLDG MKMIKGEAIA GDIPTLSLIV GFIAAFVSGC LACKWMINIV 

       250        260 
KKGKLIYFAI YCAIVGVVTI VVSQLQ 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR626927 Genomic DNA. Translation: CAH05846.1.
RefSeqYP_209808.1. NC_003228.3.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272559.BF0068.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAH05846; CAH05846; BF9343_0067.
GeneID3288204.
KEGGbfs:BF0068.
PATRIC21036596. VBIBacFra29119_0065.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
KOK06153.
OMAMGASKRS.
OrthoDBEOG6QP13M.
ProtClustDBCLSK823439.

Enzyme and pathway databases

BioCycBFRA272559:GKF0-67-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_BACFN
AccessionPrimary (citable) accession number: Q5LJ30
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: June 21, 2005
Last modified: February 19, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families