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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei143GTPUniRule annotation1
Binding sitei147GTPUniRule annotation1
Binding sitei190GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28GTPUniRule annotation5
Nucleotide bindingi112 – 114GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, SeptationUniRule annotation

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciBFRA272559:GKF0-248-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
ORF Names:BF9343_0246Imported
OrganismiBacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)Imported
Taxonomic identifieri272559 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000006731 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi272559.BF0250.

Structurei

3D structure databases

ProteinModelPortaliQ5LIK1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 208TubulinInterPro annotationAdd BLAST193
Domaini210 – 329Tubulin_CInterPro annotationAdd BLAST120

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili328 – 357Sequence analysisAdd BLAST30

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiMSIFARM.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01135. FTSZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5LIK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDEIVQFDFP TDSPKIIKVI GVGGGGGNAV NHMYREGIHD VTFVLCNTDN
60 70 80 90 100
QALAESPVPV KLQLGRSITQ GLGAGNRPER ARDAAEESIE DIKTLLNDGT
110 120 130 140 150
KMVFITAGMG GGTGTGAAPV IARIAKEMDI LTVGIVTIPF IFEGEKKIIQ
160 170 180 190 200
ALDGVERIAQ HVDALLVINN ERLREIYSDL TFMNAFGKAD DTLSIAAKSI
210 220 230 240 250
AEIITMRGTV NLDFADVKTI LKDGGVAIMS TGFGEGENRV TKAIDDALHS
260 270 280 290 300
PLLNNNDIFN AKKVMLNVSF CPASELMMEE MNEVHEFMSK FREGVEVIWG
310 320 330 340 350
VAMDNSLDTK VKITVLATGF GVEDVPGMDD LHEKRSQEEE ERQLQLEEEK
360 370 380 390 400
EKNKERIRKA YGESASGIGT RNLRKRRHIY LFNAEDLDND DIIAMVEDSP
410 420 430
TYLRDKTTLG KIKAKAALEE EIATEEAIDD SGVITF
Length:436
Mass (Da):47,811
Last modified:June 21, 2005 - v1
Checksum:i73D3DFBB49953E64
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR626927 Genomic DNA. Translation: CAH06025.1.
RefSeqiWP_005783997.1. NC_003228.3.

Genome annotation databases

EnsemblBacteriaiCAH06025; CAH06025; BF9343_0246.
KEGGibfs:BF9343_0246.
PATRICi21036956. VBIBacFra29119_0243.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR626927 Genomic DNA. Translation: CAH06025.1.
RefSeqiWP_005783997.1. NC_003228.3.

3D structure databases

ProteinModelPortaliQ5LIK1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272559.BF0250.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAH06025; CAH06025; BF9343_0246.
KEGGibfs:BF9343_0246.
PATRICi21036956. VBIBacFra29119_0243.

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiMSIFARM.

Enzyme and pathway databases

BioCyciBFRA272559:GKF0-248-MONOMER.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01135. FTSZ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5LIK1_BACFN
AccessioniPrimary (citable) accession number: Q5LIK1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 21, 2005
Last sequence update: June 21, 2005
Last modified: November 30, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.