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Q5LI65

- GLSA_BACFN

UniProt

Q5LI65 - GLSA_BACFN

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Protein
Glutaminase
Gene
glsA, BF0394
Organism
Bacteroides fragilis (strain ATCC 25285 / NCTC 9343)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei69 – 691Substrate By similarity
Binding sitei120 – 1201Substrate By similarity
Binding sitei165 – 1651Substrate By similarity
Binding sitei172 – 1721Substrate By similarity
Binding sitei196 – 1961Substrate By similarity
Binding sitei248 – 2481Substrate By similarity
Binding sitei266 – 2661Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciBFRA272559:GKF0-386-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:BF0394
OrganismiBacteroides fragilis (strain ATCC 25285 / NCTC 9343)
Taxonomic identifieri272559 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
ProteomesiUP000006731: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 321321GlutaminaseUniRule annotation
PRO_1000048323Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi272559.BF0394.

Structurei

3D structure databases

ProteinModelPortaliQ5LI65.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000022730.
KOiK01425.
OMAiMMDVSQI.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5LI65-1 [UniParc]FASTAAdd to Basket

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MDKKISISQI KEVVQQAYEQ VKGNTGGKNA DYIPYLANID KNLFGISVCL    50
LNGQTITVGD FDYRFGIESV SKVHTAILIL RQYGAQKVLE MIGADATGLP 100
FNSIIAILLE NDHPSTPLVN AGAISACSMV TPIGNSDKKW DAIVQNITDL 150
CGSAPQLIEE LYKSETATNF NNRSIAWLLK NYNRIYDDPN MSLDLYTRQC 200
SLGVTAQMLS VAAGTVANGG VNPVTKKQVF DAELTPKITS MIATVGFYEH 250
SGDWMYTSGI PAKTGVGGGV MGVLPGVFGV SAFAPPLDGS GNSVKAQLAI 300
KYIMNKLGLN VFNGARVTIV D 321
Length:321
Mass (Da):34,369
Last modified:June 21, 2005 - v1
Checksum:i56E079A059346DBF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR626927 Genomic DNA. Translation: CAH06162.1.
RefSeqiYP_210123.1. NC_003228.3.

Genome annotation databases

EnsemblBacteriaiCAH06162; CAH06162; BF9343_0383.
GeneIDi3286808.
KEGGibfs:BF0394.
PATRICi21037250. VBIBacFra29119_0389.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR626927 Genomic DNA. Translation: CAH06162.1 .
RefSeqi YP_210123.1. NC_003228.3.

3D structure databases

ProteinModelPortali Q5LI65.
ModBasei Search...

Protein-protein interaction databases

STRINGi 272559.BF0394.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAH06162 ; CAH06162 ; BF9343_0383 .
GeneIDi 3286808.
KEGGi bfs:BF0394.
PATRICi 21037250. VBIBacFra29119_0389.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000022730.
KOi K01425.
OMAi MMDVSQI.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci BFRA272559:GKF0-386-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25285 / NCTC 9343.

Entry informationi

Entry nameiGLSA_BACFN
AccessioniPrimary (citable) accession number: Q5LI65
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 21, 2005
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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