ID   ACKA_BACFN              Reviewed;         398 AA.
AC   Q5LI41;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-JUN-2005, sequence version 1.
DT   16-JUN-2009, entry version 22.
DE   RecName: Full=Acetate kinase;
DE            EC=2.7.2.1;
DE   AltName: Full=Acetokinase;
GN   Name=ackA; OrderedLocusNames=BF0424;
OS   Bacteroides fragilis (strain ATCC 25285 / NCTC 9343).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=272559;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15746427; DOI=10.1126/science.1107008;
RA   Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G.,
RA   Abratt V., Lennard N., Poxton I., Duerden B., Harris B., Quail M.A.,
RA   Barron A., Clark L., Corton C., Doggett J., Holden M.T.G., Larke N.,
RA   Line A., Lord A., Norbertczak H., Ormond D., Price C.,
RA   Rabbinowitsch E., Woodward J., Barrell B.G., Parkhill J.;
RT   "Extensive DNA inversions in the B. fragilis genome control variable
RT   gene expression.";
RL   Science 307:1463-1465(2005).
CC   -!- CATALYTIC ACTIVITY: ATP + acetate = ADP + acetyl phosphate.
CC   -!- CATALYTIC ACTIVITY: ATP + propanoate = ADP + propanoyl phosphate.
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA
CC       biosynthesis; acetyl-CoA from acetate: step 1/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the acetokinase family.
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DR   EMBL; CR626927; CAH06187.1; -; Genomic_DNA.
DR   RefSeq; YP_210147.1; -.
DR   GeneID; 3289091; -.
DR   GenomeReviews; CR626927_GR; BF0424.
DR   KEGG; bfs:BF0424; -.
DR   HOGENOM; Q5LI41; -.
DR   OMA; Q5LI41; SSDFRDV.
DR   BioCyc; BFRA272559:BF0424-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008776; F:acetate kinase activity; IEA:HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006082; P:organic acid metabolic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:HAMAP.
DR   HAMAP; MF_00020; -; 1.
DR   InterPro; IPR000890; Acetate_kin.
DR   InterPro; IPR004372; AckA.
DR   PANTHER; PTHR21060; Acetate_kin; 1.
DR   PANTHER; PTHR21060:SF11; AckA; 1.
DR   Pfam; PF00871; Acetate_kinase; 1.
DR   PIRSF; PIRSF000722; Acetate_prop_kin; 1.
DR   PRINTS; PR00471; ACETATEKNASE.
DR   TIGRFAMs; TIGR00016; ackA; 1.
DR   PROSITE; PS01075; ACETATE_KINASE_1; 1.
DR   PROSITE; PS01076; ACETATE_KINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN         1    398       Acetate kinase.
FT                                /FTId=PRO_1000002209.
SQ   SEQUENCE   398 AA;  43028 MW;  6DE0C4B55787E457 CRC64;
     MKVLVLNCGS SSIKYKLFDM DSKEVIAQGG IEKIGLKDSF LKLTLPNGEK KILEKDIPEH
     TVGVEFILNT LVSPEYGAIQ SLEEINAVGH RMVHGGERFS KSVLLTKEVL EAFAACNDLA
     PLHNPANLKG VDAITAILPN VPQIGVFDTA FHQTMPEHAY LYAIPYELYK KYGVRRYGFH
     GTSHRYVSQR VCEYLGIKPE GLKLITCHIG NGGSIAAIKD GKCIDTSMGL TPLEGLMMGT
     RSGDIDAGAV TFIMDKEGLT TTGISNLLNK KSGVAGMMNG SSDMRDLEAA VAKGDPQAIL
     TEQMYFYRIK KYIGAYAAAL GGVDVILFTG GVGENQATCR AGVCEGLEFL GVKLDPEKNK
     VRGEEAIIST DDSRVKVVVI PTDEELLIAS DTMAILDK
//