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Q5LHP3 (Q5LHP3_BACFN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase I HAMAP MF_01877
EC=2.1.1.198 HAMAP MF_01877
Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferase HAMAP MF_01877
rRNA (cytidine-2'-O-)-methyltransferase RsmI HAMAP MF_01877
Gene names
Name:rsmI HAMAP MF_01877
Ordered Locus Names:BF0585
ORF Names:BF9343_0558 EMBL CAH06337.1
OrganismBacteroides fragilis (strain ATCC 25285 / NCTC 9343) [Complete proteome] [HAMAP] EMBL CAH06337.1
Taxonomic identifier272559 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length224 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA By similarity. HAMAP MF_01877

Catalytic activity

S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytosine(1402) in 16S rRNA. HAMAP MF_01877

Subcellular location

Cytoplasm By similarity HAMAP MF_01877.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmI family. HAMAP MF_01877

Ontologies

Keywords
   Biological processrRNA processing HAMAP MF_01877
   Cellular componentCytoplasm HAMAP MF_01877
   LigandS-adenosyl-L-methionine HAMAP MF_01877
   Molecular functionMethyltransferase HAMAP MF_01877 EMBL CAH06337.1
Transferase
   Technical term3D-structure PDB 3FFY
Complete proteome
Gene Ontology (GO)
   Biological processenzyme-directed rRNA 2'-O-methylation

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionrRNA (cytosine-2'-O-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q5LHP3 [UniParc].

Last modified June 21, 2005. Version 1.
Checksum: 0388FFBD455A09AD

FASTA22424,929
        10         20         30         40         50         60 
MGKLYVVPTP VGNLEDMTFR AIKVLKEADL ILAEDTRTSG ILLKHFEIKN VMQSHHKFNE 

        70         80         90        100        110        120 
HKTVESVVNR IKAGETIALI SDAGTPGISD PGFLVVRECV RNGIEVQCLP GATAFVPALV 

       130        140        150        160        170        180 
ASGLPNEKFC FEGFLPQKKG RMTKLKSLVD EHRTMVFYES PHRLLKTLTQ FAEYFGPERQ 

       190        200        210        220 
VSVSREISKI HEETVRGTLS ELIEHFTATD PRGEIVIVLA GIDD

« Hide

References

« Hide 'large scale' references
[1]"Extensive DNA inversions in the B. fragilis genome control variable gene expression."
Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G., Abratt V., Lennard N., Poxton I., Duerden B., Harris B., Quail M.A., Barron A., Clark L., Corton C., Doggett J., Holden M.T.G., Larke N., Line A., Lord A. expand/collapse author list , Norbertczak H., Ormond D., Price C., Rabbinowitsch E., Woodward J., Barrell B.G., Parkhill J.
Science 307:1463-1465(2005) [PubMed: 15746427] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"X-ray crystal structure of putative tetrapyrrole (corrin/porphyrin) methyltransferase from Bacteroides fragilis."
Osipiuk J., Volkart L., Cobb G., Kim Y., Joachimiak A.
Submitted (DEC-2008) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 112-224.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR626927 Genomic DNA. Translation: CAH06337.1.
RefSeqYP_210295.1. NC_003228.3.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3FFYX-ray2.00A112-224[»]
ProteinModelPortalQ5LHP3.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5LHP3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3288310.
GenomeReviewsGene locus BF0585 in contig CR626927_GR.
KEGGbfs:BF0585.
PATRIC21037632. VBIBacFra29119_0574.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0313.
HOGENOMHBG529058.
OMAGREMTKI.
ProtClustDBCLSK823102.

Family and domain databases

HAMAPMF_01877. 16SrRNA_methyltr_I.
[Tree]
InterProIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR008189. rRNA_ssu_MeTfrase_I.
IPR018063. SAM_MeTrfase_RsmI_CS.
[Graphical view]
Gene3DG3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit.
G3DSA:3.30.950.10. 4pyrrole_Mease_sub2. 1 hit.
KOK07056.
PANTHERPTHR21091:SF18. PTHR21091:SF18. 1 hit.
PfamPF00590. TP_methylase. 1 hit.
[Graphical view]
PIRSFPIRSF005917. MTase_YraL. 1 hit.
SUPFAMSSF53790. Cor/por_Metransf. 1 hit.
TIGRFAMsTIGR00096. TIGR00096. 1 hit.
PROSITEPS01296. RSMI. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ5LHP3_BACFN
AccessionPrimary (citable) accession number: Q5LHP3
Entry history
Integrated into UniProtKB/TrEMBL: June 21, 2005
Last sequence update: June 21, 2005
Last modified: December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info