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Q5LH12 (PYRF_BACFN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:BF0831
OrganismBacteroides fragilis (strain ATCC 25285 / NCTC 9343) [Complete proteome] [HAMAP]
Taxonomic identifier272559 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides

Protein attributes

Sequence length274 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPyrimidine biosynthesis
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' UMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

'de novo' pyrimidine nucleobase biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionorotidine-5'-phosphate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 274274Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01215
PRO_1000138943

Sites

Active site961Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5LH12 [UniParc].

Last modified June 21, 2005. Version 1.
Checksum: 4C92B3DE82D61504

FASTA27430,634
        10         20         30         40         50         60 
MNKQSLFENI KRKKSFLCVG LDTDIKKIPD HLLDDPDPIF AFNKAIVDAT ADYCIAYKPN 

        70         80         90        100        110        120 
LAFYESMGVK GWIAFEKTVN YIKENYPDQF IIADAKRGDI GNTSAMYART FFEELDIDSV 

       130        140        150        160        170        180 
TVAPYMGEDS VTPFLSYEGK WVILLALTSN KGSHDFQLTE DANGERLFEK VLKKSQEWAN 

       190        200        210        220        230        240 
DEQMMYVVGA TQGRAFEDIR KIVPNHFLLV PGIGAQGGSL EEVCKYGMNS TCGLIVNSSR 

       250        260        270 
GIIYVDKTEN FAAAARAAAK EVQEQMAEQL KAIL 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR626927 Genomic DNA. Translation: CAH06574.1.
RefSeqYP_210526.1. NC_003228.3.

3D structure databases

ProteinModelPortalQ5LH12.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272559.BF0831.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAH06574; CAH06574; BF9343_0793.
GeneID3288837.
KEGGbfs:BF0831.
PATRIC21038132. VBIBacFra29119_0822.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0284.
HOGENOMHOG000250283.
KOK01591.
OMADATHHLC.
OrthoDBEOG6DZF33.

Enzyme and pathway databases

BioCycBFRA272559:GKF0-804-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
ProtoNetSearch...

Entry information

Entry namePYRF_BACFN
AccessionPrimary (citable) accession number: Q5LH12
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 21, 2005
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways