Q5LFH6 (Q5LFH6_BACFN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183

Gene names

Name:	ald EMBL CAH07118.1
Ordered Locus Names:	BF1406
ORF Names:	BF9343_1337 EMBL CAH07118.1

Organism

Bacteroides fragilis (strain ATCC 25285 / NCTC 9343) [Complete proteome] [HAMAP] EMBL CAH07118.1

Taxonomic identifier

272559 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	369 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183
Pathway	Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183
Sequence similarities	Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
Ligand	NAD PIRNR PIRNR000183
Molecular function	Oxidoreductase PIRNR PIRNR000183 EMBL CAH07118.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alanine dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5LFH6 [UniParc]. Last modified June 21, 2005. Version 1. Checksum: 6257D2C0E779E0CF	FASTA	369	39,703
	10 20 30 40 50 60 MIIGVPKEIK NNENRVGMTP SGVAELVKRG HTVYIQHTAG ENSGFQDEAY TAVGAQILPT 70 80 90 100 110 120 MEETYAMAQM IVKVKEPIAP EYRLIRKGQL LFTYFHFASD RELTLAMIEN GSVCLAYETV 130 140 150 160 170 180 EKADHSLPLL IPMSEVAGRM AIQEGARFLE KPQGGKGILP GGVPGVKPAK VLILGGGIVG 190 200 210 220 230 240 SNAAQMAAGL GADVTIADIN LSRLRYLSET LPKNVKTLYA SEVRLKKELP DVDLVVGSVL 250 260 270 280 290 300 IPGDKAPHLI TRDMLKMMQP GTVLVDVAID QGGCFETSHP TTHSEPTYVV DGIVHYAVAN 310 320 330 340 350 360 IPGAVPYTST LALTNATLPY VIALANKGWR KACKEDPALA LGLNVVEGKV VYRAIADVFG LKYEQLNLE

References

[1]

"Extensive DNA inversions in the B. fragilis genome control variable gene expression." Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G., Abratt V., Lennard N., Poxton I., Duerden B., Harris B., Quail M.A., Barron A., Clark L., Corton C., Doggett J., Holden M.T.G., Larke N., Line A., Lord A. , Norbertczak H., Ormond D., Price C., Rabbinowitsch E., Woodward J., Barrell B.G., Parkhill J. Science 307:1463-1465(2005) [PubMed: 15746427] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR626927 Genomic DNA. Translation: CAH07118.1.
RefSeq	YP_211062.1. NC_003228.3.
3D structure databases
ProteinModelPortal	Q5LFH6.
SMR	Q5LFH6. Positions 1-360.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5LFH6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3289087.
GenomeReviews	Gene locus BF1406 in contig CR626927_GR.
KEGG	bfs:BF1406.
PATRIC	21039255. VBIBacFra29119_1376.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0686.
HOGENOM	HBG289735.
OMA	VAHGHEV.
ProtClustDB	CLSK822772.
Family and domain databases
InterPro	IPR008142. Ala_DH/PNT_CS1. IPR008143. Ala_DH/PNT_CS2. IPR008141. Ala_DH/Pyr_transHydgase. IPR007886. AlaDH/PNT_N. IPR007698. AlaDH/PNT_NAD(H)-bd. [Graphical view]
KO	K00259.
PANTHER	PTHR10160:SF3. PTHR10160:SF3. 1 hit.
Pfam	PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view]
PIRSF	PIRSF000183. Alanine_dh. 1 hit.
SMART	SM01002. AlaDh_PNT_C. 1 hit. SM01003. AlaDh_PNT_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00518. AlaDH. 1 hit.
PROSITE	PS00836. ALADH_PNT_1. 1 hit. PS00837. ALADH_PNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5LFH6_BACFN

Accession

Primary (citable) accession number: Q5LFH6

Entry history

Integrated into UniProtKB/TrEMBL:	June 21, 2005
Last sequence update:	June 21, 2005
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)