ID   Q5LCG5_BACFN            Unreviewed;       341 AA.
AC   Q5LCG5; A0A380YZK7;
DT   21-JUN-2005, integrated into UniProtKB/TrEMBL.
DT   21-JUN-2005, sequence version 1.
DT   27-MAR-2024, entry version 92.
DE   SubName: Full=Aerotolerance-related membrane protein {ECO:0000313|EMBL:CAH08200.1};
GN   Name=batB {ECO:0000313|EMBL:CAH08200.1};
GN   ORFNames=BF9343_2419 {ECO:0000313|EMBL:CAH08200.1};
OS   Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019
OS   / NCTC 9343 / Onslow).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=272559 {ECO:0000313|EMBL:CAH08200.1, ECO:0000313|Proteomes:UP000006731};
RN   [1] {ECO:0000313|EMBL:CAH08200.1, ECO:0000313|Proteomes:UP000006731}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 /
RC   Onslow {ECO:0000313|Proteomes:UP000006731};
RX   PubMed=15746427; DOI=10.1126/science.1107008;
RA   Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G., Abratt V.,
RA   Lennard N., Poxton I., Duerden B., Harris B., Quail M.A., Barron A.,
RA   Clark L., Corton C., Doggett J., Holden M.T.G., Larke N., Line A., Lord A.,
RA   Norbertczak H., Ormond D., Price C., Rabbinowitsch E., Woodward J.,
RA   Barrell B.G., Parkhill J.;
RT   "Extensive DNA inversions in the B. fragilis genome control variable gene
RT   expression.";
RL   Science 307:1463-1465(2005).
RN   [2] {ECO:0007829|PDB:4JDU}
RP   X-RAY CRYSTALLOGRAPHY (1.47 ANGSTROMS) OF 85-296 IN COMPLEX WITH CALCIUM.
RA   Fan Y., Tan K., Bigelow L., Bearden J., Joachimiak A.;
RT   "The crystal structure of an aerotolerance-related membrane protein from
RT   Bacteroides fragilis NCTC 9343 with multiple mutations to serines.";
RL   Submitted (FEB-2013) to the PDB data bank.
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DR   EMBL; CR626927; CAH08200.1; -; Genomic_DNA.
DR   RefSeq; WP_010993034.1; NZ_UFTH01000001.1.
DR   PDB; 4JDU; X-ray; 1.47 A; A=85-296.
DR   PDBsum; 4JDU; -.
DR   PaxDb; 272559-BF9343_2419; -.
DR   DNASU; 3288979; -.
DR   KEGG; bfs:BF9343_2419; -.
DR   eggNOG; COG2304; Bacteria.
DR   HOGENOM; CLU_024570_1_0_10; -.
DR   BioCyc; BFRA272559:G1GHZ-2626-MONOMER; -.
DR   Proteomes; UP000006731; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR024163; Aerotolerance_reg_N.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR22550:SF5; LEUCINE ZIPPER PROTEIN 4; 1.
DR   PANTHER; PTHR22550; SPORE GERMINATION PROTEIN; 1.
DR   Pfam; PF07584; BatA; 1.
DR   Pfam; PF00092; VWA; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:4JDU}; Calcium {ECO:0007829|PDB:4JDU};
KW   Membrane {ECO:0000256|SAM:Phobius}; Metal-binding {ECO:0007829|PDB:4JDU};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006731};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        59..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        307..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   BINDING         99
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0007829|PDB:4JDU"
FT   BINDING         101
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0007829|PDB:4JDU"
FT   BINDING         170
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0007829|PDB:4JDU"
FT   BINDING         198
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0007829|PDB:4JDU"
SQ   SEQUENCE   341 AA;  37969 MW;  3CE6FA92CA2B4F1D CRC64;
     MFRFEEPAYL YLLLLLPLLA AFYLYSNYRK RKAIRKFGDP VLMAQLMPDV SKYRPDVKFW
     LLFTAIGLFA VLLARPQFGS KLETVKRKGV EVMIALDISN SMLAQDVQPS RLEKAKRLIS
     KLVDGMENDK VGMIVFAGDA FTQLPITSDY ISAKMFLESI SPSLISKQGT AIGAAINLAA
     RSFTPQEGVG RAIVVITDGE NHEGGAVEAA KEAAKKGIQV NVLGVGLPDG APIPIEGSND
     FRRDREGNVI VTRLNEAMCQ EIAKEGNGIY IRVDNSNSAQ KAINQEINKM AKSDVESKVY
     TDYNEQFQVI AWMILLLLLV EMLILDRKNP LFKNIRLFSN K
//