Q5LBZ4 (Q5LBZ4_BACFN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Indole-3-glycerol phosphate synthase EMBL CAH08374.1
EC=4.1.1.48 EMBL CAH08374.1

Gene names

Name:	trpC EMBL CAH08374.1
Ordered Locus Names:	BF2676
ORF Names:	BF9343_2593 EMBL CAH08374.1

Organism

Bacteroides fragilis (strain ATCC 25285 / NCTC 9343) [Complete proteome] [HAMAP] EMBL CAH08374.1

Taxonomic identifier

272559 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	270 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. SAAS SAAS013798
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. SAAS SAAS013798

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis SAAS SAAS013798
Molecular function	Decarboxylase SAAS SAAS013798 Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5LBZ4 [UniParc]. Last modified June 21, 2005. Version 1. Checksum: 8F1E463C548F121D	FASTA	270	29,902
	10 20 30 40 50 60 MKDILSEIIA NKRFEIDLQK QAIPSEQLQE KLSDEVQPGY SMKQALASSA TGIIAEFKRR 70 80 90 100 110 120 SPSKGWIYEN ACPEQVVPDY IAAGASALSI LTDEKFFGGS LKDIRTARPL VNIPILRKDF 130 140 150 160 170 180 IIDEYQLFQA KIVGADAILL IAAALEADQC HALAAKAHEL GLEVLLEIHT AEELPFINKE 190 200 210 220 230 240 IDMVGINNRN LGTFFTDVEN SFRLAGQLPQ DALLVSESGI SDPETVKRLR KAGFRGFLIG 250 260 270 ETFMKTQQPG QKLKEFINDL NSPQSDTESH

References

[1]

"Extensive DNA inversions in the B. fragilis genome control variable gene expression." Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G., Abratt V., Lennard N., Poxton I., Duerden B., Harris B., Quail M.A., Barron A., Clark L., Corton C., Doggett J., Holden M.T.G., Larke N., Line A., Lord A. , Norbertczak H., Ormond D., Price C., Rabbinowitsch E., Woodward J., Barrell B.G., Parkhill J. Science 307:1463-1465(2005) [PubMed: 15746427] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR626927 Genomic DNA. Translation: CAH08374.1.
RefSeq	YP_212295.1. NC_003228.3.
3D structure databases
ProteinModelPortal	Q5LBZ4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5LBZ4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3285221.
GenomeReviews	Gene locus BF2676 in contig CR626927_GR.
KEGG	bfs:BF2676.
PATRIC	21041924. VBIBacFra29119_2689.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0134.
HOGENOM	HBG540956.
OMA	VESLGMT.
ProtClustDB	PRK00278.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GlycerolPSynthase_CS. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01609.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5LBZ4_BACFN

Accession

Primary (citable) accession number: Q5LBZ4

Entry history

Integrated into UniProtKB/TrEMBL:	June 21, 2005
Last sequence update:	June 21, 2005
Last modified:	December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)