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Protein

Beta-galactosidase

Gene

BF9343_2998

Organism
Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationSAAS annotation, Hydrolase

Enzyme and pathway databases

BioCyciBFRA272559:GKF0-3041-MONOMER.

Protein family/group databases

CAZyiGH2. Glycoside Hydrolase Family 2.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseUniRule annotationSAAS annotation (EC:3.2.1.23UniRule annotationSAAS annotation)
Alternative name(s):
LactaseUniRule annotation
Gene namesi
ORF Names:BF9343_2998Imported
OrganismiBacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)Imported
Taxonomic identifieri272559 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
ProteomesiUP000006731 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi272559.BF3084.

Structurei

3D structure databases

ProteinModelPortaliQ5LAU4.
SMRiQ5LAU4. Positions 27-1020.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 2 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3250.
HOGENOMiHOG000252444.
KOiK01190.
OMAiAIIPSFW.
OrthoDBiEOG6XWV0T.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSiPR00132. GLHYDRLASE2.
SMARTiSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMiSSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEiPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5LAU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKPIKLTFL LILACLMLLP VNAQNTPEWQ SQYAVGLNKL APHTYVWPYA
60 70 80 90 100
SATDVKKGDY EQSPYYLNLN GKWKFHWVKN PDLRPKDFYK PSFYTGGWAD
110 120 130 140 150
INVPGNWERQ GYGTAIYVNE TYEFDDKMFN FKKNPPLVPY KENEVGSYRR
160 170 180 190 200
TFTVPAGWKG RRVVLCCEGV ISFYYVWVNG HFLGYNQGSK TAAEWDITDQ
210 220 230 240 250
LEEGENTIAL EVYRWSSGSY LECQDMWRLS GIERDVYLYS TPKQYIADYK
260 270 280 290 300
VNATLEKERY KDGIFGLDVT VGGPADGVAS VSYTLNDPLG RPVLSGEMPV
310 320 330 340 350
KSRGLSNFIT FGEQRLKDVK RWSAEHPNLY TLVLELKNAG GQVTEVTGCE
360 370 380 390 400
VGFRTSEIKD GRFCINGVPV LVKGTNRHEH SQLGRTVSKE LMEQDIRLMK
410 420 430 440 450
LYNINTVRNS HYPTDPYWYR LCDRYGLYMI DEANIESHGM GYGPASLAKD
460 470 480 490 500
STWLTAHMDR THRMYERSKN HPAIVIWSLG NEAGNGINFE RTYDWLKSVE
510 520 530 540 550
KSRPVQYERA EQNYNTDIYC RMYRSVDEIK AYLAQKDIYR PFILCEYVHA
560 570 580 590 600
MGNSVGGLKE YWDVFENNPM AQGGCVWDWV DQSFREIDSN GRWYWSYGGD
610 620 630 640 650
YGPKGIPSFG NFCCNGLVSA DRVPHPHLLE VKKIYQNIKC TLINKNNLTV
660 670 680 690 700
RVKNWFDFSN LNEYILHWQV VGDNGKLLAE GNKEVNCAPH ATADVTLGKV
710 720 730 740 750
ALPANVREGY LNLSWTRKEA SPMVGTDWEV AYDQFVLPGT KGSTAYLPAK
760 770 780 790 800
AGQTAFTVDK ETGALNSLTL DGQELLATPV TLSLFRPATD NDNRDRNGAY
810 820 830 840 850
LWRKAGLNQL TQKVVSLKDG KKAATAKVEI LNAKGMKVGD ADFAYSLNSA
860 870 880 890 900
GALKVKVTFR PDTAVVKSMA RLGLTFEMND TYGNVAYLGR GDNETYSDRM
910 920 930 940 950
QSGKIALYQT TAERMFHYYV TPQSTGNRTD VRWMKLTDET GQGIFVDSNR
960 970 980 990 1000
PFQFSVIPFA DDVLEKARHI NDLERNGHVT VHLDAEQAGV GTATCGPGVQ
1010 1020
PQYRVPVTEQ SFEFTLRTVK
Length:1,020
Mass (Da):115,699
Last modified:June 21, 2005 - v1
Checksum:i25592484915B2179
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR626927 Genomic DNA. Translation: CAH08779.1.
RefSeqiWP_010993256.1. NC_003228.3.
YP_212697.1. NC_003228.3.

Genome annotation databases

EnsemblBacteriaiCAH08779; CAH08779; BF9343_2998.
KEGGibfs:BF9343_2998.
PATRICi21042798. VBIBacFra29119_3118.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR626927 Genomic DNA. Translation: CAH08779.1.
RefSeqiWP_010993256.1. NC_003228.3.
YP_212697.1. NC_003228.3.

3D structure databases

ProteinModelPortaliQ5LAU4.
SMRiQ5LAU4. Positions 27-1020.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272559.BF3084.

Protein family/group databases

CAZyiGH2. Glycoside Hydrolase Family 2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAH08779; CAH08779; BF9343_2998.
KEGGibfs:BF9343_2998.
PATRICi21042798. VBIBacFra29119_3118.

Phylogenomic databases

eggNOGiCOG3250.
HOGENOMiHOG000252444.
KOiK01190.
OMAiAIIPSFW.
OrthoDBiEOG6XWV0T.

Enzyme and pathway databases

BioCyciBFRA272559:GKF0-3041-MONOMER.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSiPR00132. GLHYDRLASE2.
SMARTiSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMiSSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEiPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343Imported.

Entry informationi

Entry nameiQ5LAU4_BACFN
AccessioniPrimary (citable) accession number: Q5LAU4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 21, 2005
Last sequence update: June 21, 2005
Last modified: May 27, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.