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Q5L9J7 (Q5L9J7_BACFN) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446
EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL CAH09230.1
Ordered Locus Names:BF3542
ORF Names:BF9343_3449 EMBL CAH09230.1
OrganismBacteroides fragilis (strain ATCC 25285 / NCTC 9343) [Complete proteome] [HAMAP] EMBL CAH09230.1
Taxonomic identifier272559 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides ›

Protein attributes

Sequence length396 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
Q5L9J7 [UniParc].

Last modified June 21, 2005. Version 1.
Checksum: D02DAEEA34F996BF

FASTA39643,596
        10         20         30         40         50         60 
MSKITKQQNG VLSVPDVPTI PFITGDGVGA EITPAMQAIV DAAVDMSYGG VRRIEWKEVL 

        70         80         90        100        110        120 
AGERAFRATG SWLPDETMEV FKEYLIGIKG PLTTPVGGGI RSLNVALRQT LDLYVCLRPV 

       130        140        150        160        170        180 
RWFRGVVSPV KEPEKVKMYI FRENTEDIYA GIEWEAGTPE AKKFYRFLHE EMGVSKVRFP 

       190        200        210        220        230        240 
ETSSFGVKPV SREGTERLVR AACRYALQHE LPSVTLVHKG NIMKFTEGGF KKWGYELAER 

       250        260        270        280        290        300 
EFADALASGK LVIKDCIADA FLQNTLLIPE EYSVIATLNL NGDYISDQLA AMVGGIGIAP 

       310        320        330        340        350        360 
GANINYDSGH AIFEATHGTA PNIAGKNVVN PCSLILSAVM MLEYIGWQEP ADLIVEALEA 

       370        380        390 
SFAEGKATND LARFMHKGQP LSTSEFTREI INRIKN

« Hide

References

[1]"Extensive DNA inversions in the B. fragilis genome control variable gene expression."
Cerdeno-Tarraga A.-M., Patrick S., Crossman L.C., Blakely G., Abratt V., Lennard N., Poxton I., Duerden B., Harris B., Quail M.A., Barron A., Clark L., Corton C., Doggett J., Holden M.T.G., Larke N., Line A., Lord A. expand/collapse author list , Norbertczak H., Ormond D., Price C., Rabbinowitsch E., Woodward J., Barrell B.G., Parkhill J.
Science 307:1463-1465(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25285 / NCTC 9343.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR626927 Genomic DNA. Translation: CAH09230.1.
RefSeqYP_213144.1. NC_003228.3.

3D structure databases

ProteinModelPortalQ5L9J7.
SMRQ5L9J7. Positions 9-393.
ModBaseSearch...

Protein-protein interaction databases

STRING272559.BF3542.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAH09230; CAH09230; BF9343_3449.
GeneID3287902.
KEGGbfs:BF3542.
PATRIC21043812. VBIBacFra29119_3616.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0538.
HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.
ProtClustDBCLSK823004.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ5L9J7_BACFN
AccessionPrimary (citable) accession number: Q5L9J7
Entry history
Integrated into UniProtKB/TrEMBL: June 21, 2005
Last sequence update: June 21, 2005
Last modified: May 1, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info