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Q5L9E3 (G6PI_BACFN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:BF3604
OrganismBacteroides fragilis (strain ATCC 25285 / NCTC 9343) [Complete proteome] [HAMAP]
Taxonomic identifier272559 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides

Protein attributes

Sequence length445 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 445445Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180596

Sites

Active site2871Proton donor By similarity
Active site3081 By similarity
Active site4221 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5L9E3 [UniParc].

Last modified June 21, 2005. Version 1.
Checksum: D2112CB217B7C65C

FASTA44548,750
        10         20         30         40         50         60 
MISLNIEKTF GFISKESVSA YEAQVKAAQE ALENGTGKGN DFLGWLHLPS SISKEHLADL 

        70         80         90        100        110        120 
KATAQVLRDN CEVVIVAGIG GSYLGARAVI EALSNSFTWL QEKKTAPVMI YAGHNIGEDY 

       130        140        150        160        170        180 
LYELTEFLKD KKFGVINISK SGTTTETALA FRLLKKQCED QRGKEMAKKV IVAVTDAKKG 

       190        200        210        220        230        240 
AARVTADKEG YKSFIIPDNV GGRFSVLTPV GLLPIAVAGF DIEQLVNGAA DMEKACGADV 

       250        260        270        280        290        300 
PFAENPAAIY AATRNELYKN GKKIEILVNF CPKLHYVSEW WKQLYGESEG KDNKGIFPAA 

       310        320        330        340        350        360 
VDFSTDLHSM GQWIQEGERT IFETVISVDK VNHKLEVPSD EANLDGLNFL AGKRVDEVNK 

       370        380        390        400        410        420 
MAELGTQLAH VDGGVPNMRI VIPELSEFSI GQLLYFFEKA CGISGYLLGV NPFNQPGVEA 

       430        440 
YKKNMFALLN KPGYEEESKA IQARL 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR626927 Genomic DNA. Translation: CAH09285.1.
RefSeqYP_213198.1. NC_003228.3.

3D structure databases

ProteinModelPortalQ5L9E3.
SMRQ5L9E3. Positions 2-445.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272559.BF3604.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAH09285; CAH09285; BF9343_3504.
GeneID3287829.
KEGGbfs:BF3604.
PATRIC21043934. VBIBacFra29119_3677.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000100403.
KOK01810.
OMAFGIINIS.
OrthoDBEOG64R61J.
ProtClustDBPRK14097.

Enzyme and pathway databases

BioCycBFRA272559:GKF0-3555-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_BACFN
AccessionPrimary (citable) accession number: Q5L9E3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: June 21, 2005
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways