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Q5L6K4 (GLGB_CHLAB) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:CAB262
OrganismChlamydophila abortus (strain DSM 27085 / S26/3) [Complete proteome] [HAMAP]
Taxonomic identifier218497 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydophila

Protein attributes

Sequence length721 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7217211,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_0000260643

Sites

Active site4001Nucleophile By similarity
Active site4531Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5L6K4 [UniParc].

Last modified June 21, 2005. Version 1.
Checksum: 5E4CBEFF46AF64A6

FASTA72183,023
        10         20         30         40         50         60 
MVERIVNSED VSLLVSGRQS NPHKFLGIVS ENSSQDRIIL FRPGAHSVVV ELQGNIAHAQ 

        70         80         90        100        110        120 
HHHSGIFSLT APKGTLPQDY RIYHQNGLLA HDPYAFPPLW GEVDSFLFHQ GTHYKIYECM 

       130        140        150        160        170        180 
GAIPYNVQGI SGVLFVVWAP HAQRVSVVGD FNFWNGLVNP LRKVSDLGVW ELFIPGLEEG 

       190        200        210        220        230        240 
TLYKWEIVSA SGEVLIKTDP YGKRFDVPPH APSRVVDSDR YTWHDAAWME KRKHRGDQPL 

       250        260        270        280        290        300 
AIYEVHVGSW QWHEGKPLGY RELAKKLAAY CKEMHYTHVE LLPVTEHPLN ESWGYQVTGY 

       310        320        330        340        350        360 
YAPTCRYGTP EDFQFFVDHL HRENIGVILD WVPGHFPTDG FALAHFDGEA LYESIENHEP 

       370        380        390        400        410        420 
LHPHWRTYTF DYRCNEVVNF LLGSALFWLD KMHIDGLRVD AVTSMLYLDY GRQEGEWSPN 

       430        440        450        460        470        480 
IYGGRENLQA IEFIKHLNSV VHREFPGVLT FAEESTDFPK VTQAVAQGGL GFDYKWNLGW 

       490        500        510        520        530        540 
MHDTFRYIQV DPLFRSYHHK DLTFSLWYAF NERYLLPLSH DEVVHGKGSL LQKMPGDTWT 

       550        560        570        580        590        600 
KFAHMRLLLS YHICQPGKKL LFMGGEFAQG KEWTPDSPLD WHLLDHPDHA YLHKCVARMN 

       610        620        630        640        650        660 
ALYCDLPYFW KGDGKQGSFR WVDFKDTENH VIAYYRFSGE DRSSALLCVH HFSSGYFPSY 

       670        680        690        700        710        720 
VLYCQDIHSC QLLFNSDDCC FGGSGKGNRQ PVLCLDQHVS WGIDIELPPL ATLIFHVDFV 


N 

« Hide

References

[1]"The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation."
Thomson N.R., Yeats C., Bell K., Holden M.T.G., Bentley S.D., Livingstone M., Cerdeno-Tarraga A.-M., Harris B., Doggett J., Ormond D., Mungall K., Clarke K., Feltwell T., Hance Z., Sanders M., Quail M.A., Price C., Barrell B.G., Parkhill J., Longbottom D.
Genome Res. 15:629-640(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 27085 / S26/3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR848038 Genomic DNA. Translation: CAH63718.1.
RefSeqYP_219688.1. NC_004552.2.

3D structure databases

ProteinModelPortalQ5L6K4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING218497.CAB262.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAH63718; CAH63718; CAB262.
GeneID3338056.
KEGGcab:CAB262.
PATRIC20201942. VBIChlAbo21869_0290.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAKWEIVTA.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycCABO218497:GJB0-275-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_CHLAB
AccessionPrimary (citable) accession number: Q5L6K4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: June 21, 2005
Last modified: June 11, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries