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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Chlamydia abortus (strain DSM 27085 / S26/3) (Chlamydophila abortus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciCABO218497:GJB0-312-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:CAB304
OrganismiChlamydia abortus (strain DSM 27085 / S26/3) (Chlamydophila abortus)
Taxonomic identifieri218497 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000001012 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 555555Exodeoxyribonuclease 7 large subunitPRO_0000273651Add
BLAST

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Protein-protein interaction databases

STRINGi218497.CAB304.

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229265.
KOiK03601.
OMAiDFNENFA.
OrthoDBiPOG091H02EK.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 2 hits.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5L6H1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATSSPPQAV TTLTESIKNL LESNFCHIVV KGELSNVSLQ PSGHLYFGIK
60 70 80 90 100
DSKSFLNGAF FHFKSKYFDR RPKDGDSVII HGKLTVYAPR GQYQIVAHAL
110 120 130 140 150
VYAGEGDLLQ KFEETKKRLA AEGYFSIEKK QPLPRIPKCI GVITSPTGAV
160 170 180 190 200
IQDILRILSR RCYQYKVLIY PVTVQGATAA KEISQAIEVM NRDKLVDVLV
210 220 230 240 250
IARGGGSIED LWAFNEEIIV KAIDASTIPI ISAVGHETDY TLCDFAADVR
260 270 280 290 300
APTPSAAGEI VCQSSQEQIQ IFKSHLRYLN AHAQQLLAGK AKQIQQWKRY
310 320 330 340 350
LDHVDFFRPP HQSLDYLRVS IERSIQTTLS QSKQRYRQYT RWLQSDILQR
360 370 380 390 400
MTYRLQDLWK MINLAFQNRL LALKHHCVHI KKNLVIHNTQ QYRQRFDPCR
410 420 430 440 450
DQIHRALSQR LGYFQQSLAH KQTLLKHFTT KINQLFIKET SALNLLKKRL
460 470 480 490 500
NKAFVYTVCE RREHFLYAKE NLFLSLNHLV ERHRAKYHTV SQQLISLNPK
510 520 530 540 550
NVLKRGYAML FDFNENSAII SAKSLHKHSC VRVRLQDGEA TLTVTDVQNF

ETQEF
Length:555
Mass (Da):63,857
Last modified:June 21, 2005 - v1
Checksum:i26EE66D5AA83B5B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR848038 Genomic DNA. Translation: CAH63754.1.
RefSeqiWP_011096971.1. NC_004552.2.

Genome annotation databases

EnsemblBacteriaiCAH63754; CAH63754; CAB304.
KEGGicab:CAB304.
PATRICi20202039. VBIChlAbo21869_0337.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR848038 Genomic DNA. Translation: CAH63754.1.
RefSeqiWP_011096971.1. NC_004552.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi218497.CAB304.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAH63754; CAH63754; CAB304.
KEGGicab:CAB304.
PATRICi20202039. VBIChlAbo21869_0337.

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229265.
KOiK03601.
OMAiDFNENFA.
OrthoDBiPOG091H02EK.

Enzyme and pathway databases

BioCyciCABO218497:GJB0-312-MONOMER.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 2 hits.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiEX7L_CHLAB
AccessioniPrimary (citable) accession number: Q5L6H1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: June 21, 2005
Last modified: September 7, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.