Reviewed,
UniProtKB/Swiss-Prot Q5L6E3 (RNC_CHLAB)
Last modified
February 9, 2010.
Version 27.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Ribonuclease 3 EC=3.1.26.3 Alternative name(s): Ribonuclease III Short name=RNase III | ||||
| Gene names |
| ||||
| Organism | Chlamydophila abortus [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 83555 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydophila |
Protein attributes
| Sequence length | 237 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs By similarity. HAMAP MF_00104 |
| Catalytic activity | Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP MF_00104 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00104. |
| Sequence similarities | Contains 1 DRBM (double-stranded RNA-binding) domain. Contains 1 RNase III domain. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Ligand | RNA-binding |
| Molecular function | Endonuclease Hydrolase Nuclease |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | mRNA processing Inferred from electronic annotation. Source: HAMAP rRNA catabolic processInferred from electronic annotation. Source: InterPro rRNA processingInferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | double-stranded RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease III activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 237 | 237 | Ribonuclease 3 HAMAP MF_00104 | PRO_0000228514 | |||||
Regions | |||||||||
| Domain | 7 – 135 | 129 | RNase III | ||||||
| Domain | 160 – 229 | 70 | DRBM | ||||||
Sequences
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References
| [1] | "The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation." Thomson N.R., Yeats C., Bell K., Holden M.T.G., Bentley S.D., Livingstone M., Cerdeno-Tarraga A.-M., Harris B., Doggett J., Ormond D., Mungall K., Clarke K., Feltwell T., Hance Z., Sanders M., Quail M.A., Price C., Barrell B.G., Parkhill J., Longbottom D. Genome Res. 15:629-640(2005) [PubMed: 15837807] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S26/3. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CR848038 Genomic DNA. Translation: CAH63783.1. |
| RefSeq | YP_219749.1. |
3D structure databases | |
| SMR | Q5L6E3. Positions 6-226. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3338091. |
| GenomeReviews | Gene locus CAB334 in contig CR848038_GR. |
| KEGG | cab:CAB334. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG744556. |
| OMA | SAYANLF. |
Enzyme and pathway databases | |
| BioCyc | CABO218497:CAB334-MONOMER. |
| BRENDA | 3.1.26.3. 292247. |
Family and domain databases | |
| HAMAP | MF_00104. RNase_III. [Tree] |
| InterPro | IPR001159. Ds-RNA_bd. IPR014720. dsRNA-bd-like. IPR000999. RNase_III. IPR011907. RNase_III_bac. [Graphical view] |
| Gene3D | G3DSA:3.30.160.20. dsRNA-bd-like. 1 hit. G3DSA:1.10.1520.10. RNase_III. 1 hit. |
| Pfam | PF00035. dsrm. 1 hit. PF00636. Ribonuclease_3. 1 hit. [Graphical view] |
| SMART | SM00358. DSRM. 1 hit. SM00535. RIBOc. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR02191. RNaseIII. 1 hit. |
| PROSITE | PS50137. DS_RBD. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | RNC_CHLAB | ||||||||
| Accession | Primary (citable) accession number: Q5L6E3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

Clusters with


