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Q5L6B8 (Q5L6B8_CHLAB) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chromosomal replication initiator protein DnaA 1 HAMAP MF_00377
Gene names
Name:dnaA1 HAMAP MF_00377
Ordered Locus Names:CAB358
OrganismChlamydophila abortus [Complete proteome] [HAMAP]
Taxonomic identifier83555 [NCBI]
Taxonomic lineageBacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydophila

Protein attributes

Sequence length450 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377 RuleBase RU000577

Subcellular location

Cytoplasm By similarity HAMAP MF_00377.

Sequence similarities

Belongs to the DnaA family. HAMAP MF_00377 RuleBase RU004227

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding156 – 1638ATP By similarity HAMAP MF_00377

Sequences

Sequence LengthMass (Da)Tools
Q5L6B8 [UniParc].

Last modified June 21, 2005. Version 1.
Checksum: 822EF696B4D28360

FASTA45051,242
        10         20         30         40         50         60 
MLTCSDCSTW EQFVNYVKTR CSKTAFENWI SPIQIIEETQ EKIRLEVPNI FVQNYLLDNY 

        70         80         90        100        110        120 
KQDLCSFVPL DAQGEPALEF VVAEIKKAPP QPVAPREQQE TPIETFEESK DFELKLNTAY 

       130        140        150        160        170        180 
RFDNFIEGPS NQFVKSAAVG IAGRPGRSYN PLFIHGGVGL GKTHLLHAVG HYVREHHKNL 

       190        200        210        220        230        240 
RVHCITTEAF INDLVQHLRL KSIDKMKNFY RSLDLLLVDD IQFLQNRQNF EEEFCNTFET 

       250        260        270        280        290        300 
LINLNKQIVI TSDKPPGQLK LSERIIARME WGLVAHVGIP DLETRVAILQ HKAEQKGLHI 

       310        320        330        340        350        360 
PNEIAFYIAD HIYGNVRQLE GAINKLTAYC RLFGKTLTET IVRDTLKELF RSPSKQKVSV 

       370        380        390        400        410        420 
ESILKSVATV FQVKLQELKG NSRSKELVLA RQVAMYLAKT LITDSLVAIG SAFGKTHSTV 

       430        440        450 
LYACKTIEQK IEKDETLTRQ ISLCKNHIVG

« Hide

References

[1]"The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation."
Thomson N.R., Yeats C., Bell K., Holden M.T.G., Bentley S.D., Livingstone M., Cerdeno-Tarraga A.-M., Harris B., Doggett J., Ormond D., Mungall K., Clarke K., Feltwell T., Hance Z., Sanders M., Quail M.A., Price C., Barrell B.G., Parkhill J., Longbottom D.
Genome Res. 15:629-640(2005) [PubMed: 15837807] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: S26/3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR848038 Genomic DNA. Translation: CAH63809.1.
RefSeqYP_219774.1. NC_004552.2.

3D structure databases

ProteinModelPortalQ5L6B8.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3338153.
GenomeReviewsGene locus CAB358 in contig CR848038_GR.
KEGGcab:CAB358.
PATRIC20202163. VBIChlAbo21869_0399.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG695666.
OMACHTLNAL.
PhylomeDBQ5L6B8.
ProtClustDBPRK00149.

Family and domain databases

HAMAPMF_00377. DnaA_bact.
[Tree]
InterProIPR003593. ATPase_AAA+_core.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013159. DnaA_C.
IPR013317. DnaA_Hda.
IPR010921. Trp_repressor/repl_initiator.
[Graphical view]
Gene3DG3DSA:1.10.1750.10. DnaA_C. 1 hit.
KOK02313.
PfamPF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
[Graphical view]
PRINTSPR00051. DNAA.
SMARTSM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
[Graphical view]
SUPFAMSSF48295. Trp_repress_rep. 1 hit.
TIGRFAMsTIGR00362. DnaA. 1 hit.
PROSITEPS01008. DNAA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ5L6B8_CHLAB
AccessionPrimary (citable) accession number: Q5L6B8
Entry history
Integrated into UniProtKB/TrEMBL: June 21, 2005
Last sequence update: June 21, 2005
Last modified: January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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