Q5L687 (DCD_CHLAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	CAB391

Organism

Chlamydophila abortus (strain S26/3) [Complete proteome] [HAMAP]

Taxonomic identifier

218497 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Chlamydiae/Verrucomicrobia group › Chlamydiae › Chlamydiia › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydophila › Chlamydophila abortus

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 190	190	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000009703

Sequences

	Sequence		Length	Mass (Da)
	Q5L687 [UniParc]. Last modified June 21, 2005. Version 1. Checksum: 28588D39C9750925	FASTA	190	21,572
	10 20 30 40 50 60 MSIKEDKWIR KMALAHGMIE PFADGQVNLN PETGEKLISY GLSSYGYDLR LSREFKVFTN 70 80 90 100 110 120 VYNSLVDPKR FTEDTFISIT DDVCIIPPNS FALAHSVEYF RIPRNVLTMC IGKSTYARCG 130 140 150 160 170 180 LIVNVTPFEP EWEGYVTIEI SNTTPLPAKI YANEGIAQVL FFEADEICEV SYAERKGKYQ 190 KQQGITVPFV

References

[1]

"The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation." Thomson N.R., Yeats C., Bell K., Holden M.T.G., Bentley S.D., Livingstone M., Cerdeno-Tarraga A.-M., Harris B., Doggett J., Ormond D., Mungall K., Clarke K., Feltwell T., Hance Z., Sanders M., Quail M.A., Price C., Barrell B.G., Parkhill J., Longbottom D. Genome Res. 15:629-640(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S26/3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR848038 Genomic DNA. Translation: CAH63844.1.
RefSeq	YP_219805.1. NC_004552.2.
3D structure databases
ProteinModelPortal	Q5L687.
ModBase	Search...
Protein-protein interaction databases
STRING	218497.CAB391.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAH63844; CAH63844; CAB391.
GeneID	3337641.
KEGG	cab:CAB391.
PATRIC	20202251. VBIChlAbo21869_0442.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228600.
KO	K01494.
OMA	RSVLTVC.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	CABO218497:GJB0-403-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CHLAB

Accession

Primary (citable) accession number: Q5L687

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	June 21, 2005
Last modified:	May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program